5PSQ-096 Hazard vulnerability analysis to evaluate the risk of drug shortages according to therapeutic class

Giammona, R; Martino, E Di; Vinci, Daniele Leonardi; Provenzani, A; Polidori, Piera

doi:10.1136/ejhpharm-2020-eahpconf.413

Cited by 2 publications

(1 citation statement)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…A reporting and tracking system can report all related aspects of a drug shortage, including its period, drugs involved, frequency, duration, causes, impacts, managing strategies, and predict future shortages. Such a system should be present at every institution (Giammona et al, 2020) as done by the Drug Shortage Program (DSP) developed by the FDA in 1990 (Dill and Ahn, 2014;Said et al, 2018) and Texas Medical Board (Mazer-Amirshahi et al, 2014). The databases and public websites are found in many middle and high-income countries of the European Union, the United States, and Western Asian countries.…”

Section: Improvement In Operationsmentioning

confidence: 99%

Drug Shortage: Causes, Impact, and Mitigation Strategies

et al. 2021

View full text Add to dashboard Cite

Drug shortage is a global issue affecting low, middle, and high-income countries. Many countries have developed various strategies to overcome the problem, while the problem is accelerating, affecting the whole world. All types of drugs, such as essential life-saving drugs, oncology medicines, antimicrobial drugs, analgesics, opioids, cardiovascular drugs, radiopharmaceutical, and parenteral products, are liable to the shortage. Among all pharmaceutical dosage forms, sterile injectable products have a higher risk of shortage than other forms. The causes of shortage are multifactorial, including supply issues, demand issues, and regulatory issues. Supply issues consist of manufacturing problems, unavailability of raw materials, logistic problems, and business problems. In contrast, demand issues include just-in-time inventory, higher demand for a product, seasonal demand, and unpredictable demand. For regulatory issues, one important factor is the lack of a unified definition of drug shortage. Drug shortage affects all stakeholders from economic, clinical, and humanistic aspects. WHO established global mitigation strategies from four levels to overcome drug shortages globally. It includes a workaround to tackle the current shortage, operational improvements to reduce the shortage risk and achieve early warning, changes in governmental policies, and education and training of all health professionals about managing shortages.

show abstract

Section: Improvement In Operationsmentioning

confidence: 99%

Drug Shortage: Causes, Impact, and Mitigation Strategies

et al. 2021

View full text Add to dashboard Cite

show abstract

Effective Supply Chain Strategies in Addressing Demand and Supply Uncertainty: A Case Study of Ethiopian Pharmaceutical Supply Services

Bilal,

Bititci,

Fenta

2024

Pharmacy

View full text Add to dashboard Cite

Background: Ensuring the consistent availability of essential medicines is crucial for effective healthcare systems. However, Ethiopian public health facilities have faced frequent stockouts of crucial medications, highlighting systemic challenges such as inadequate forecasting, prolonged procurement processes, a disjointed distribution system, suboptimal data quality, and a shortage of trained professionals. This study focuses on the Ethiopian Pharmaceutical Supply Services (EPSS), known for its highly unstable and volatile supply chain, aiming to identify risks and mitigation strategies. Methods: Using a mixed-method approach involving surveys and interviews, the research investigates successful and less successful strategies, key success factors, and barriers related to pharmaceutical shortages. Results: Proactive measures such as communication, stock assessment, supervision, and streamlined procurement are emphasized as vital in mitigating disruptions, while reactive strategies like safety stock may lack long-term efficacy. The study highlights the importance of aligning supply chain strategies with product uncertainties, fostering collaboration, and employing flexible designs for resilience. Managerial implications stress the need for responsive structures that integrate data quality, technology, and visibility. Conclusions: This study contributes by exploring proactive and reactive strategies, elucidating key success factors for overcoming shortages in countries with unstable supply chains, and offering actionable steps for enhancing supply chain resilience. Embracing uncertainty and implementing proactive measures can help navigate volatile environments, thereby enhancing competitiveness and sustainability.

show abstract

5PSQ-096 Hazard vulnerability analysis to evaluate the risk of drug shortages according to therapeutic class

Cited by 2 publications

References 0 publications

Drug Shortage: Causes, Impact, and Mitigation Strategies

Drug Shortage: Causes, Impact, and Mitigation Strategies

Effective Supply Chain Strategies in Addressing Demand and Supply Uncertainty: A Case Study of Ethiopian Pharmaceutical Supply Services

Contact Info

Product

Resources

About