5PSQ-057 Development of an analysis method to assess the occupational risk dealing with therapeutic monoclonal antibodies using liquid chromatography and high-resolution mass spectrometry (lc-hrms)
Abstract:BackgroundIn the last decade biopharmaceuticals became increasingly important. In 2016, nine out of 10 top-selling drugs were classified as biologics and their market share is still growing. The risk assessment of biopharmaceuticals from the occupational health perspective, however, is not completed. Especially the role of therapeutic monoclonal antibodies (mAbs) for occupational safety is still discussed controversially. In this debate it becomes clear that the large molecular weight hinders mAbs to penetrate… Show more
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