594 Localisation Failures with Radio-guided Occult Lesion Localisation; Pitfalls and Solutions

Incidence and Risk Factors of the Intraoperative Localization Failure of Nonpalpable Breast Lesions by Radio‐guided Occult Lesion Localization: A Retrospective Analysis of 579 Cases: Reply

“…As this was a retrospective study the authors propose that prospective studies are required to affirm their findings.Recently we performed a prospective randomized controlled trial in which we compared 162 patients who underwent ROLL with 152 patients who underwent wireguided localization (WGL) for non-palpable breast cancers [2]. Of all patients who underwent ROLL, five (3 %) localization failures (i.e., defined as \25 % of the lesion enclosed in the surgical specimen) were encountered [3]. When comparing our prospective results with the results of Bernardi and colleagues, we show a similar proportion of localization failures.Bernardi et al found that the main risk factors for failure were lesion size \5 mm, radiologist's inexperience, and tumor located in the central subareolar quadrant.…”

“…Recently we performed a prospective randomized controlled trial in which we compared 162 patients who underwent ROLL with 152 patients who underwent wire‐guided localization (WGL) for non‐palpable breast cancers [2]. Of all patients who underwent ROLL, five (3 %) localization failures (i.e., defined as <25 % of the lesion enclosed in the surgical specimen) were encountered [3]. When comparing our prospective results with the results of Bernardi and colleagues, we show a similar proportion of localization failures.…”