581 Predictors of Adequate Biopsy Sampling in Patients with Barrett's Esophagus: Analysis of a National Community-Based Gastrointestinal Pathology Database

Endoscopic diagnosis and treatment of upper gastrointestinal tumors

“…Methods to improve the yield for dysplasia during Barrett's esophagus surveillance Surveillance endoscopies with random biopsy for Barrett's esophagus dysplasia are expensive and time consuming, which could explain why adher− ence to recommended biopsy protocols is incom− plete. Analysis of a large United States (US) com− munity−based pathology database showed that adequate biopsy sampling was performed in only 670 (48.3 %) of 1386 cases of Barrett's eso− phagus surveillance endoscopy, with patient age of 70 years or older and long−segment Barrett's esophagus being significant predictors of inade− quate sampling on multivariable analysis [22]. New methods for targeted biopsy are being sought to replace random biopsy; it is anticipated that targeted biopsy will detect more dysplasia and more advanced dysplasia using fewer tissue samples.…”