56 Cytosponge Evaluation of Eosinophilic Esophagitis in Comparison to Endoscopy: Accuracy, Safety and Tolerability

Katzka, David A.; Ravi, Anupama; Geno, Debra M.; Smyrk, Thomas C.; Kita, Hirohito; Lao‐Sirieix, Pierre; Beecham, Irene Debiram; Kephart, Gail M.; Kryzer, Lori A.; Alexander, Jeffrey A.; Fitzgerald, Rebecca

doi:10.1016/s0016-5085(14)60056-1

Cited by 4 publications

(3 citation statements)

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“…New less invasive ways of measuring histological response including the aforementioned tethered confocal endomicroscopy capsule, measuring luminal eosinophilderived proteins on a swallowed string [129] or a newly developed swallowed, tethered cytosponge, which can provide histological samples, may assist in this measurement [130]. For patients with fibrostenotic disease, esophageal wall distensibility can be followed using a novel technique called impedance planimetry [131] or functional luminal imaging probe (FLIP), in which a bag filled with a solution and passed through the esophagus, measuring both luminal diameter and distensability [132].…”

Section: Endpoints In Treatmentmentioning

confidence: 99%

Eosinophilic Esophagitis: A Comprehensive Review

Nt¹

2016

J Hepatol Gastroint Dis

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Eosinophilic Esophagitis (EoE) has been the subject of intense research and study over the past few years, as incidence and prevalence has increased in the United States, especially in adults. The signs, symptoms and complications of EoE arise from a complex interplay of genetic predisposition and environmental exposure that is not understood well at this time. The disease causes significant morbidity in both physical and psychological areas, and these effects may become permanent in some cases where remodeling of the epithelium is present. Treatment at this time mainly focuses on diet, medication and endoscopic dilation. While none of these entities can accomplish all of the treatment goals, careful selection of patients based on symptoms and physical findings can alleviate many of the complications of the disease. In addition, this review attempts to cull data from adult studies if possible, as much of the studies that involved children did not translate well to adult patients.

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Section: Endpoints In Treatmentmentioning

confidence: 99%

Eosinophilic Esophagitis: A Comprehensive Review

Nt¹

2016

J Hepatol Gastroint Dis

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“…At DDW, a group from the Mayo Clinic presented results from a proof-of-concept study using the Cytosponge for minimally invasive evaluation of eosinophilic esophagitis [3]. The Cytosponge is a novel device consisting of a foam sponge compressed into a gelatin capsule, which is attached to a string [4].…”

Section: Eosinophilic Esophagitismentioning

confidence: 99%

Esophageal diseases

Wolf

Dellon

Shaheen

2014

Gastrointestinal Endoscopy

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“…[3] The Cytosponge is a novel device consisting of a foam sponge compressed into a gelatin capsule, which is attached to a string. [4] Patients swallow the capsule, but the string is kept dangling from the mouth.…”

Section: Eosinophilic Esophagitis: New Prospects For Minimally Invasimentioning

confidence: 99%