545 Oxygen saturation targeting in infants on the neonatal unit

Abstract

Results A total of 1293 infants were identified over a 5 year period between the two sites. Subgroup analysis of infants with a length of stay !28 days showed 424 out of 809 infants met biochemical criteria for MBDP (52.4%). The median time to meeting biochemical criteria was 16 days.Only 54 infants had a documented diagnosis of metabolic bone disease on BadgerNet (4% of all high-risk infants and 6.7% of infants with a length of stay !28 days); 8 of these babies did not meet biochemical criteria for MBDP.There were 5 documented fractures (2 humeral and 3 rib fractures), described as incidental findings on routine radiographs. Conclusions. The percentage of infants meeting biochemical criteria for MBDP is consistent with published incidence data. Using these biochemical criteria does not overestimate the incidence in this population. . The median time to meeting biochemical criteria is consistent with published literature and highlights the key period to screen at-risk infants. . Biochemical MBDP is under-reported on the BadgerNet database. This suggests that increased awareness of MBDP may be required or that biochemical criteria are not being routinely used to make the diagnosis. Caution should be exercised when interpreting BadgerNet data in view of this. . The documented incidence of fracture related to biochemical MBDP was 1%, well below the published incidence of 10%. This may be due to suboptimal data entry but may also be related to under-recognition of such fractures.