Untitled

Goldman, Julian M.; Petterson, Michael T.; Kopotic, Robert J.; Barker, Steven J.

doi:10.1023/a:1011493521730

Cited by 233 publications

(62 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…We tried to overcome many of the known limitations by maintaining a core temperature of 39.0-39.5°C, using dim light, good animal fixation to limit motion, shielding of the pulse oximeter sensors, continuous anesthesia, maintaining systolic arterial blood pressure of 50 mm Hg with CPR by an experienced resuscitation team, and using one of the most recently available pulse oximetry devices to limit the effects of motion and low perfusion [17]. …”

Section: Discussionmentioning

confidence: 99%

Reliability of Pulse Oximetry during Progressive Hypoxia, Cardiopulmonary Resuscitation, and Recovery in a Piglet Model of Neonatal Hypoxic Cardiac Arrest

et al. 2017

View full text Add to dashboard Cite

Background: Pulse oximetry is widely used in intensive care and emergency conditions to monitor arterial oxygenation and to guide oxygen therapy. Objective: To study the reliability of pulse oximetry in comparison with CO-oximetry in newborn piglets during progressive hypoxia, cardiac arrest, cardiopulmonary resuscitation (CPR), and after return of spontaneous circulation (ROSC). Methods: Thirty-three newborn piglets were exposed to hypoxia until asystole occurred and then resuscitated until ROSC. Arterial oxygen saturation was monitored continuously by pulse oximetry (SpO₂) with one sensor applied to the wrist of the right forelimb (FL) and another to the thigh of the left hind limb (HL). Arterial functional oxygen saturation (SaO₂) was measured at baseline and at predefined intervals during each phase of the experiment. SpO₂ was compared with coinciding SaO₂ values and bias considered whenever the difference (SpO₂ - SaO₂) was beyond ±5%. Results: Bias values were lower at the baseline measurements (-3.7 ± 2.3% in FL and -4.1 ± 3.4% in HL) as well as after ROSC (1.5 ± 4.2% in FL and 0.2 ± 4.6% in HL) with higher precision and accuracy than during other experiment phases. During hypoxia induction, cardiac arrest, and CPR, there was a marked decrease in precision and accuracy as well as an increase in bias up to 43 ± 26 and 56 ± 27% in FL and HL, respectively, over a range of SaO₂ from 13 to 51%. Conclusion: Pulse oximetry showed increased bias and decreased accuracy and precision during marked hypoxemia in a model of neonatal hypoxic cardiac arrest.

show abstract

Section: Discussionmentioning

confidence: 99%

Reliability of Pulse Oximetry during Progressive Hypoxia, Cardiopulmonary Resuscitation, and Recovery in a Piglet Model of Neonatal Hypoxic Cardiac Arrest

et al. 2017

View full text Add to dashboard Cite

show abstract

“…Several limitations of pulse oximetry represent a major challenge especially in emergency situations. We tried to overcome many of the known limitations by keeping a core temperature of 39.0-39.5°C, using dim light throughout the experiment, shielding of the pulse oximeter sensor, good fixation of the animal, use of continuous sedation, maintaining a systolic arterial blood pressure of 50 mm Hg with CPR by an experienced resuscitation team, and the use of one of the most recently available pulse oximetry devices to limit the effects of motion and low perfusion [24]. Additionally, major electrolyte disturbances (other than hyperkalemia) and hypoglycemia were prevented by continuous intravenous fluid infusion (table 1).…”

Section: Discussionmentioning

confidence: 99%

Reliability of Pulse Oximetry during Cardiopulmonary Resuscitation in a Piglet Model of Neonatal Cardiac Arrest

et al. 2014

View full text Add to dashboard Cite

Background: Pulse oximetry is widely used in intensive care and emergency conditions to monitor arterial oxygenation and to guide oxygen therapy. Objective: To study the reliability of pulse oximetry in comparison with CO-oximetry in newborn piglets during cardiopulmonary resuscitation (CPR). Methodology: In a prospective cohort study in 30 healthy newborn piglets, cardiac arrest was induced, and thereafter each piglet received CPR for 20 min. Arterial oxygen saturation was monitored continuously by pulse oximetry (SpO₂). Arterial blood was analyzed for functional oxygenation (SaO₂) every 2 min. SpO₂ was compared with coinciding SaO₂ values and bias considered whenever the difference (SpO₂ - SaO₂) was beyond ±5%. Results: Bias values were decreased at the baseline measurements (mean: 2.5 ± 4.6%) with higher precision and accuracy compared with values across the experiment. Two minutes after cardiac arrest, there was a marked decrease in precision and accuracy as well as an increase in bias up to 13 ± 34%, reaching a maximum of 45.6 ± 28.3% after 10 min over a mean SaO₂ range of 29-58%. Conclusion: Pulse oximetry showed increased bias and decreased accuracy and precision during CPR in a model of neonatal cardiac arrest. We recommend further studies to clarify the exact mechanisms of these false readings to improve reliability of pulse oximetry during the marked desaturation and hypoperfusion found during CPR. © 2014 S. Karger AG, Basel

show abstract

“…The change of the finger PI resulted from the blood volume pulsations, the dispensability of the vascular wall and the intravascular pulse pressure, which can be complicated in critically ill adult patients [22,23]. Therefore, many factors can impact the PI value (temperature, level of consciousness, pain and other stressful stimuli, endogenous catecholamines, vasopressors).…”

Section: Discussionmentioning

confidence: 99%

The peripheral perfusion index and transcutaneous oxygen challenge test are predictive of mortality in septic patients after resuscitation

Liu

Long

et al. 2013

Crit Care

View full text Add to dashboard Cite

IntroductionThe peripheral perfusion index (PI) is a noninvasive numerical value of peripheral perfusion, and the transcutaneous oxygen challenge test (OCT) is defined as the degree of transcutaneous partial pressure of oxygen (PtcO2) response to 1.0 FiO2. The value of noninvasive monitoring peripheral perfusion to predict outcome remains to be established in septic patients after resuscitation. Moreover, the prognostic value of PI has not been investigated in septic patients.MethodsForty-six septic patients, who were receiving PiCCO-Plus cardiac output monitoring, were included in the study group. Twenty stable postoperative patients were studied as a control group. All the patients inspired 1.0 of FiO2 for 10 minutes during the OCT. Global hemodynamic variables, traditional metabolic variables, PI and OCT related-variables were measured simultaneously at 24 hours after PiCCO catheter insertion. We obtained the 10min-OCT ((PtcO2 after 10 minutes on inspired 1.0 oxygen) - (baseline PtcO2)), and the oxygen challenge index ((10min-OCT)/(PaO2 on inspired 1.0 oxygen - baseline PaO2)) during the OCT.ResultsThe PI was significantly correlated with baseline PtcO2, 10min-OCT and oxygen challenge index (OCI) in all the patients. The control group had a higher baseline PtcO2, 10min-OCT and PI than the septic shock group. In the sepsis group, the macro hemodynamic parameters and ScvO2 showed no differences between survivors and nonsurvivors. The nonsurvivors had a significantly lower PI, 10min-OCT and OCI, and higher arterial lactate level. The PI, 10min-OCT and OCI predicted the ICU mortality with an accuracy that was similar to arterial lactate level. A PI <0.2 and a 10min-OCT <66mmHg were related to poor outcome after resuscitation.ConclusionsThe PI and OCT are predictive of mortality for septic patients after resuscitation. Further investigations are required to determine whether the correction of an impaired level of peripheral perfusion may improve the outcome of septic shock patients.

show abstract

Untitled

Abstract: The technological strategies implemented in Masimo SET pulse oximetry effectively permit continuous monitoring of SpO2 during challenging clinical conditions of motion and poor tissue perfusion.

Cited by 233 publications

References 21 publications

Reliability of Pulse Oximetry during Progressive Hypoxia, Cardiopulmonary Resuscitation, and Recovery in a Piglet Model of Neonatal Hypoxic Cardiac Arrest

Reliability of Pulse Oximetry during Progressive Hypoxia, Cardiopulmonary Resuscitation, and Recovery in a Piglet Model of Neonatal Hypoxic Cardiac Arrest

Reliability of Pulse Oximetry during Cardiopulmonary Resuscitation in a Piglet Model of Neonatal Cardiac Arrest

The peripheral perfusion index and transcutaneous oxygen challenge test are predictive of mortality in septic patients after resuscitation

Contact Info

Product

Resources

About