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Abstract

Because insulin and hCG may share common pathways beyond the level of receptor activation, we hypothesize that GnRH agonist, but not GnRH antagonist, may affect the expression and/or activation of LH receptors in the hGLCs.

Factors affecting Embryo Quality and Pregnancy Outcome in Intra-Cytoplasmic Sperm Injection using Decapeptyl and Cetrorelix- A retrospective study

“…17 Since GnRH antagonists have a direct effect on the steroid production in the granulosa cells of the follicles, a better quality and more mature embryo could be attributed to this treatment protocol. 18 There was no association between treatment type and pregnancy outcomes. Studies in other populations have shown a higher pregnancy rate in patients undergoing the antagonist treatment Even in the poor responder's subgroup of patients, the pregnancy rate is higher in the antagonist group.…”