50. Magnetic Resonance Imaging optimization for liver SBRT: Breath-triggered acquisition in treatment position to improve lesion contouring

Satoh, Ken; Tournier, A.; Rives, M.; Izar, F.; Aziza, R.; Morel, Nathalie; Sekkal, Y.; Parent, L.

doi:10.1016/j.ejmp.2016.11.102

Cited by 1 publication

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“…Breathing motion is another source of error in treatment planning, as traditional MRI image acquisition is relatively slow and several breathing cycles pass by the time an image is acquired, leading to image blurring. Respiratory-triggered image acquisition with the patient in the treatment position using optimised MRI sequences can improve image quality although there is the penalty of increased scan times [ 79 ]. Implantation of radio-opaque fiducial markers to guide treatment delivery and real-time tumour tracking using external intra-fraction monitoring devices are other approaches to motion management [ 80 , 81 ].…”

Section: Current Use Of Functional Mri For Liver Sbrtmentioning

confidence: 99%

Role of Functional MRI in Liver SBRT: Current Use and Future Directions

Tadimalla

Wang

Haworth

2022

Cancers

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Stereotactic body radiation therapy (SBRT) is an emerging treatment for liver cancers whereby large doses of radiation can be delivered precisely to target lesions in 3–5 fractions. The target dose is limited by the dose that can be safely delivered to the non-tumour liver, which depends on the baseline liver functional reserve. Current liver SBRT guidelines assume uniform liver function in the non-tumour liver. However, the assumption of uniform liver function is false in liver disease due to the presence of cirrhosis, damage due to previous chemo- or ablative therapies or irradiation, and fatty liver disease. Anatomical information from magnetic resonance imaging (MRI) is increasingly being used for SBRT planning. While its current use is limited to the identification of target location and size, functional MRI techniques also offer the ability to quantify and spatially map liver tissue microstructure and function. This review summarises and discusses the advantages offered by functional MRI methods for SBRT treatment planning and the potential for adaptive SBRT workflows.

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Section: Current Use Of Functional Mri For Liver Sbrtmentioning

confidence: 99%