5. Prevention or Delay of Type 2 Diabetes: Standards of Medical Care in Diabetes—2018

Abstract

The American Diabetes Association (ADA) "Standards of Medical Care in Diabetes" includes ADA's current clinical practice recommendations and is intended to provide the components of diabetes care, general treatment goals and guidelines, and tools to evaluate quality of care. Members of the ADA Professional Practice Committee, a multidisciplinary expert committee, are responsible for updating the Standards of Care annually, or more frequently as warranted. For a detailed description of ADA standards, statements, and reports, as well as the evidence-grading system for ADA's clinical practice recommendations, please refer to the Standards of Care Introduction Readers who wish to comment on the Standards of Care are invited to do so at professional.diabetes.org/SOC.

An Overview and Update on Obesity and the Obesity Paradox in Cardiovascular Diseases

“…However, until this is confirmed, the current evidence may suggest that MHO should be treated as an "at risk" medical condition, such as pre-DM, 99 for which treatment primarily involves either lifestyle modification, medications, or both, in order to prevent the development of MetS/DM and its sequelae. 100 Perhaps MHO should be considered in a similar fashion, and efforts should be made in treating those with MHO before developing metabolic abnormalities and ultimately increased risk for CVD, as a form of primary prevention.…”

Klinefelter syndrome, insulin resistance, metabolic syndrome, and diabetes: review of literature and clinical perspectives

“…DPP, consistent in lifestyle changes such as nutritional suggestions (e.g. reducing caloric intake and increasing consumption of food high in monounsaturated fats), and physical activity (exercise prescriptions designed to prevent diabetes are based on aerobic activity and may include resistance training) has provided the strongest evidence for diabetes prevention in the general population [75,76]. Moreover, the use of metformin was effective in reducing the risk of diabetes by one third in individuals at high-risk for the disease [76].…”

Metformin: A stroke of luck

“…Recently, the American Diabetes Association guidelines suggested metformin therapy could be used for the prevention of type 2 diabetes in patients with prediabetes, with BMI ≥35 kg/m2, aged <60 years, and women with prior gestational diabetes mellitus (46).…”