5-Methoxy-N,N-Diisopropyltryptamine-Induced Flashbacks

Alterations in Body Temperature, Corticosterone, and Behavior Following the Administration of 5-Methoxy-Diisopropyltryptamine (‘Foxy’) to Adult Rats: a New Drug of Abuse

“…5-MEO-DIPT was first synthesized by Shulgin and Carter (1980) and was described as inducing auditory and visual hallucinations in humans lasting 3-6 h. Emergency room reports and recent case studies confirm the auditory and visual hallucinogenic properties of 5-MEO-DIPT and suggest that the drug can also produce tactile hallucinations, agitation, tachycardia, somatic disturbance, cataleptic states, unconsciousness, flashbacks, increased glucose levels, vomiting, rhabdomyolysis, and in at least one case, seizure activity or death (Alatrash et al, 2006;Ikeda et al, 2005;Kiyota, 2004;Meatherall and Sharma, 2003;Muller, 2004;Smolinske et al, 2004;Tanaka et al, 2006;Wilson et al, 2005). From case studies, users have reported administering various amounts of the drug (ie, 10-37.5 mg) via oral or rectal routes of administration (Ikeda et al, 2005;Kiyota, 2004).…”

“…In Shulgin and Carter's initial human study, users reported effects (ie, hallucinations, etc.) when 5-MEO-DIPT was taken at a dose of 6-10 mg; however from the various case studies and other sources (eg, www.Erowid.com), it is reported that the drug is taken at higher concentrations (up to 100 mg per 'hit') and may be taken multiple times on a single day (Ikeda et al, 2005;Kiyota, 2004).…”

“…From case studies, users have reported administering various amounts of the drug (ie, 10-37.5 mg) via oral or rectal routes of administration (Ikeda et al, 2005;Kiyota, 2004). Although these doses were reported in several case studies, it is likely that they are not representative of all users, as the drug is used similarly to MDMA which is often taken in higher doses than those reported in these case studies on 5-MEO-DIPT.…”

Designer Drugs as a Cause of Homicide

“…Three clinical case reports [2][3][4] and one experimental study [5] have concerned 5-MeO-DIPT intoxication. Meatherall & Sharma [3] reported that 5-MeO-DIPT may cause mild hallucinations and motor disturbances lasting for 3.5 hours, while Wilson et al [4] reported transient tactile hallucinations resolving after 4 hours of observation in an emergency ward.…”

“…Taken together, these reports appeared to suggest that psychotic symptoms induced by 5-MeO-DIPT may be relatively transient, or lasting several hours at the most. However, Ikeda et al [2] have described auditory hypersensitivity and persistent visual distortions. No reports, however, mentioned severely disordered conduct or disturbances of consciousness induced by 5-MeO-DIPT.…”