2011
DOI: 10.1107/s1600536811005216
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(5S)-3-Chloro-5-[(1R,2S,5R)-2-isopropyl-5-methylcyclohexyloxy]-4-(4-methylpiperidin-1-yl)furan-2(5H)-one

Abstract: The title compound, C20H32ClNO3, was obtained via a tandem asymmetric Michael addition–elimination reaction of (5S)-3,4-dichloro-5-(l-menth­yloxy)furan-2(5H)-one and 4-methyl­piperidine in the presence of potassium fluoride. The furan­one ring is approximately planar [maximum atomic deviation = 0.022 (2) Å] while the cyclo­hexane ring adopts a chair conformation. Weak inter­molecular C—H⋯O hydrogen bonding is present in the crystal structure.

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