4D flow MRI derived aortic hemodynamics multi-year follow-up in repaired coarctation with bicuspid aortic valve

Soulat, Gilles; Scott, Michael B.; Pathrose, Ashitha; Jarvis, Kelly; Berhane, Haben; Allen, Bradley D.; Avery, Ryan; Roldán-Alzate, Alejandro; Rigsby, Cynthia K.; Markl, Michael

doi:10.1016/j.diii.2022.04.003

Cited by 10 publications

(2 citation statements)

References 32 publications

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“…In comparing this study to previous articles and research in the area, mortality correlation could be a useful clinical indicator to understand in relation to flow parameters. More recently, Soulat et al [ 40 ] examined aortic coarctation repair in BAV patients using 4D-flow imaging for a median of four years after repair. This study found that 4D-flow parameters were stable between serial scans.…”

Section: Clinical Applications In Bicuspid Valve Diseasementioning

confidence: 99%

Clinical Use of Blood Flow Analysis through 4D-Flow Imaging in Aortic Valve Disease

Mansoor

Garcia

2023

JCDD

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Bicuspid aortic valve (BAV), which affects 1% of the general population, results from the abnormal fusion of the cusps of the aortic valve. BAV can lead to the dilatation of the aorta, aortic coarctation, development of aortic stenosis (AS), and aortic regurgitation. Surgical intervention is usually recommended for patients with BAV and bicuspid aortopathy. This review aims to examine 4D-flow imaging as a tool in cardiac magnetic resonance imaging for assessing abnormal blood flow and its clinical application in BAV and AS. We present a historical clinical approach summarizing evidence of abnormal blood flow in aortic valve disease. We highlight how abnormal flow patterns can contribute to the development of aortic dilatation and novel flow-based biomarkers that can be used for a better understanding of the disease progression.

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Section: Clinical Applications In Bicuspid Valve Diseasementioning

confidence: 99%

Clinical Use of Blood Flow Analysis through 4D-Flow Imaging in Aortic Valve Disease

Mansoor

Garcia

2023

JCDD

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“…However, in recent years a volumetric acquisition called 4D flow MRI (4D: 3D+time) has emerged as an accurate and comprehensive technique [6] for the flow evaluation. As a matter of fact, 4D flow MRI allows a retrospective evaluation of flow volumes and velocities at any site of the acquired volume [7][8][9][10].…”

Section: Introductionmentioning

confidence: 99%

Comparison of 2D and 4D Flow MRI Measurements for Hemodynamic Evaluation of the Fontan Palliation

Listo,

Martini,

Salvadori

et al. 2023

CHD

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Background: The assessment of Fontan circuit's flow is traditionally evaluated by multiple through-plane phasecontrast MRI acquisitions (2D flow), while recently, a single volumetric 4D-flow MRI acquisition is emerging as a comprehensive tool for the hemodynamic evaluation in congenital heart diseases. Purpose: To compare 2D and 4D-flow MRI measurements in patients after Fontan palliation and to evaluate parameters affecting potential disagreement. Methods: 39 patients after Fontan palliation (23 males, age 22 ± 11 years) who underwent cardiac MRI with 2D and 4D-flow MRI acquisition were included in the study. In all patients, blood flow quantification in the Fontan circuit and aorta by 2D flow and by 4D flow MRI acquisition blinding to the 2D results was performed. The agreement between 2D and 4D-flow MRI was calculated as the intraclass correlation coefficient (ICC). The mean absolute differences between 4D and 2D flows were analyzed using linear regression models. Results: 4D-flow MRI acquisition time was slightly lower than 2D (7.6 ± 1.8 min vs. 9.4 ± 3.3 min, p = 0.03). Flow was slightly predominant in the right pulmonary artery (58% of total pulmonary flow). Conduit/tunnel-pulmonary arteries flow accounted for 60% of the Fontan circuit. Agreement between 2D and 4D was overall goodto-excellent from ICC: 0.817 95% CI: 0.637-0.907 to 0.932 95% CI: 0.866-0.965. There was no significant influence of evaluated parameters on the agreement on 4D and 2D flow. Conclusions: 4D-flow MRI represents a valid tool in Fontan's flow quantification. Further larger studies are needed to confirm our results and to evaluate the impact of advanced 4D-flow MRI parameters on the prognostic stratification in patients after Fontan palliation.

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Imaging aortic flows in 4D using MRI

van Ooij

2024

Biomechanics of the Aorta

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4D flow MRI derived aortic hemodynamics multi-year follow-up in repaired coarctation with bicuspid aortic valve

Cited by 10 publications

References 32 publications

Clinical Use of Blood Flow Analysis through 4D-Flow Imaging in Aortic Valve Disease

Clinical Use of Blood Flow Analysis through 4D-Flow Imaging in Aortic Valve Disease

Comparison of 2D and 4D Flow MRI Measurements for Hemodynamic Evaluation of the Fontan Palliation

Imaging aortic flows in 4D using MRI

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