4D Biofabrication of T‐Shaped Vascular Bifurcation

Kitana, Waseem; Apsite, Indra; Hazur, Jonas; Boccaccını, Aldo R.; Ionov, Leonid

doi:10.1002/admt.202200429

Cited by 22 publications

(28 citation statements)

References 36 publications

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“…They found that UV exposure strengthened the construct, but longer exposure decreased the tube diameter; besides, increasing gelatin concentration increased the thickness of the films. [166] Tiny tubular structures used to treat constricted vessels, for example, BVs are called stents. [167] Nearly half of the stents used are shape-memory alloys, nitinol being an example.…”

Section: D Bioprintingmentioning

confidence: 99%

4D Printing for Vascular Tissue Engineering: Progress and Challenges

Zeenat

Zolfagharian

Yeleswarapu

et al. 2023

Adv Materials Technologies

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The hierarchical network of blood vessels comprises the larger vessels (veins and arteries), the smaller ones (venules and arterioles), and the thinnest capillaries. The proper functioning of most tissues in the body relies on vascularization, which is meant for the diffusion of gases, nutrients, and harmful waste. However, it is known that cell survival is compromised as the diffusion of oxygen is limited beyond 100–200 µm and damage can occur at any level of the complex system of the vascular network, as is the case in cardiovascular, musculoskeletal, and neurovascular diseases that recur and progress with age. These may prove fatal, hence the need for vascular tissue engineering (VTE) arises. VTE mainly focuses on the fabrication of vascular constructs using natural, synthetic material, or a combination of both using various techniques. The construct is expected to integrate and anastomose with the host vasculature. 4D bioprinting is an emerging field that allows the fabrication of hollow tubes employing different materials that respond to different stimuli. This review is a comprehensive summary of the major techniques employed in VTE and the recent technique of 4D bioprinting foreseen to revolutionize the field.

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Section: D Bioprintingmentioning

confidence: 99%

4D Printing for Vascular Tissue Engineering: Progress and Challenges

Zeenat

Zolfagharian

Yeleswarapu

et al. 2023

Adv Materials Technologies

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“…Recently, an exciting and intensively explored area of research in advanced biomaterials is prototyping/fabrication systems [ 43 ]. The advantages of biofabrication are complete control of the geometry and porosity of materials and no need to use additional porogen to obtain a scaffold.…”

Section: Selected Biomaterials Based On Cage-like Silsesquioxanesmentioning

confidence: 99%

A Brief Review on Selected Applications of Hybrid Materials Based on Functionalized Cage-like Silsesquioxanes

John

Ejfler

2023

Polymers

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Rapid developments in materials engineering are accompanied by the equally rapid development of new technologies, which are now increasingly used in various branches of our life. The current research trend concerns the development of methods for obtaining new materials engineering systems and searching for relationships between the structure and physicochemical properties. A recent increase in the demand for well-defined and thermally stable systems has highlighted the importance of polyhedral oligomeric silsesquioxane (POSS) and double-decker silsesquioxane (DDSQ) architectures. This short review focuses on these two groups of silsesquioxane-based materials and their selected applications. This fascinating field of hybrid species has attracted considerable attention due to their daily applications with unique capabilities and their great potential, among others, in biomaterials as components of hydrogel networks, components in biofabrication techniques, and promising building blocks of DDSQ-based biohybrids. Moreover, they constitute attractive systems applied in materials engineering, including flame retardant nanocomposites and components of the heterogeneous Ziegler-Natta-type catalytic system.

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“…B‐I) Adapted under the terms of the CC‐BY Creative Commons Attribution 4.0 International license ( https://creativecommons.org/licenses/by/4.0). [ 118 ] Copyright 2022, The Authors, published by Wiley‐VCH. B‐II) Adapted with permission.…”

Section: Self‐assembly and Interconnection Of (Folded) Microelectroni...mentioning

confidence: 99%

“…Secondly, SMARTLETs can also roll or fold up to contain chemical fluids without leakage as demonstrated already. [118,145] Thus, they can contain chemical resources and prevent access to external chemicals to their interior. It remains to be demonstrated that self-assembled SMARTLETs can make tight seals to retain fluids in folded sheets.…”

Section: How This Technology Addresses the Core Functions Of Cells An...mentioning

confidence: 99%

Microelectronic Morphogenesis: Smart Materials with Electronics Assembling into Artificial Organisms

McCaskill,

Karnaushenko,

Zhu

et al. 2023

Advanced Materials

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Microelectronic morphogenesis is the creation and maintenance of complex functional structures by microelectronic information within shape‐changing materials. Only recently has in‐built information technology begun to be used to reshape materials and their functions in three dimensions to form smart microdevices and microrobots. Electronic information that controls morphology is inheritable like its biological counterpart, genetic information, and is set to open new vistas of technology leading to artificial organisms when coupled with modular design and self‐assembly that can make reversible microscopic electrical connections. Three core capabilities of cells in organisms, self‐maintenance (homeostatic metabolism utilizing free energy), self‐containment (distinguishing self from nonself), and self‐reproduction (cell division with inherited properties), once well out of reach for technology, are now within the grasp of information‐directed materials. Construction‐aware electronics can be used to proof‐read and initiate game‐changing error correction in microelectronic self‐assembly. Furthermore, noncontact communication and electronically supported learning enable one to implement guided self‐assembly and enhance functionality. Here, the fundamental breakthroughs that have opened the pathway to this prospective path are reviewed, the extent and way in which the core properties of life can be addressed are analyzed, and the potential and indeed necessity of such technology for sustainable high technology in society is discussed.

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4D Biofabrication of T‐Shaped Vascular Bifurcation

Cited by 22 publications

References 36 publications

4D Printing for Vascular Tissue Engineering: Progress and Challenges

4D Printing for Vascular Tissue Engineering: Progress and Challenges

A Brief Review on Selected Applications of Hybrid Materials Based on Functionalized Cage-like Silsesquioxanes

Microelectronic Morphogenesis: Smart Materials with Electronics Assembling into Artificial Organisms

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