Twisted conformal symmetries are used to construct families of SU(2)-instantons on noncommutative (isospectral) toric four-spheres. §1. Toric noncommutative manifolds Toric noncommutative manifolds -introduced in 6) and called isospectral deformations -are deformations of classical Riemannian manifolds M satisfying all the properties of noncommutative spin geometry. 4) The main idea consists in deforming the spectral triple of the Riemannian geometry of M along a torus embedded in the isometry group, thus obtaining families of noncommutative geometries.Let (M, g) be an m-dimensional compact Riemannian spin manifold equipped with an isometric smooth action σ of an n-torus T n , n ≥ 2. We denote by σ also the corresponding action of T n by automorphisms on the algebra C ∞ (M ) of smooth functions on M . The algebra C ∞ (M ) is decomposed 17) into spectral subspaces which are indexed by the dual group Z n = T n . With s = (s 1 , . . . , s n ) ∈ T n , each r ∈ Z n labels a character e 2πis → e 2πir·s of T n , where r · s := n j=1 r j s j . The r-th spectral subspace for the action σ is made of those smooth functions f r for which σ s (f r ) = e 2πir·s f r , (1 . 1) and each f ∈ C ∞ (M ) is the sum of a unique rapidly convergent series f = r f r . With θ = (θ jk ) a real antisymmetric n × n matrix, the θ-deformation of C ∞ (M ) is obtained by replacing the usual product by a deformed one. On spectral subspaces:2) extended linearly to the whole of C ∞ (M ). We denote C ∞ (M θ ) := (C ∞ (M ), × θ ) which still carries an action σ of T n given by (1 . 1) on the homogeneous elements. Next, let H := L 2 (M, S) be the Hilbert space of spinors and D / the usual Dirac operator of the metric g of M . Smooth functions act on spinors by pointwise multiplication, thus giving a representation π : C ∞ (M ) → B(H), the latter being the algebra of bounded operators on H. There is a double cover c : T n → T n and a representation of T n on H by unitary operators U (s), s ∈ T n , so that