49. The Association Between Admission Blood Pressure and Outcomes in Patients With Acute Coronary Syndrome

Abstract

Background:In patients with acute coronary syndrome (ACS), the role of admission blood pressure (BP) on outcomes remains inconclusive.Objective:This study aimed to investigate the association between admission BP and various outcomes in patients hospitalized for ACS.Method:In this cross-sectional study, 279 patients who admitted with ACS to Kediri District Hospital and Bogor General Hospital between January and June 2020 were included. Data were analyzed using SPSS software v25.Result:There was association between hypertension status on admission and diagnosis; there were more hypertensive patients with non-ST segment elevation (NSTE) ACS compared to ST segment elevation (STE) ACS diagnosis (p = 0.002); and significant difference on admission systolic BP between STE-ACS and NSTE-ACS patients (p < 0.00001). Patients who died during hospitalization had significantly lower admission systolic BP compared to survived patients (p = 0.001). Patients with reduced ejection fraction (EF) on follow-up echocardiography had significantly lower admission systolic BP compared to patients with normal EF (p = 0.014). Patients with diastolic dysfunction on follow-up echocardiography had significantly higher admission systolic BP compared to patients without diastolic dysfunction (p = 0.009). No significant difference on length of stay between hypertensive and non-hypertensive patients (p = 0.416).Conclusion:Lower admission systolic BP was associated with increased in-hospital mortality and reduced EF, while higher systolic BP was associated with diastolic dysfunction.