468 Baseline Heart Rate and Adverse Outcomes in Patients With Atrial Fibrillation: A Combined Affirm and AF-CHF Sub-Study

Pharmacological treatment of atrial fibrillation in the context of heart failure poses numerous challenges. Management decisions are limited by contraindications to several drugs and the paucity of robust clinical trials that provide evidence-based guidance. This review proposes a structured action plan for managing atrial fibrillation coexisting with heart failure that considers published clinical guidelines and integrates recent data derived from substudies of randomized trials, including the atrial fibrillation and congestive heart failure (AF-CHF) trial. Areas of uncertainty, such as target heart rates in atrial fibrillation and upstream therapies, are also discussed.

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Atrial fibrillation in heart failure: drug therapies for rate and rhythm control

Tadros

Khairy

Rouleau

et al. 2013

Heart Fail Rev

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Challenging the status quo: β-blockers for HF plus AF

Khairy

Roy

2014

Nat Rev Cardiol

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468 Baseline Heart Rate and Adverse Outcomes in Patients With Atrial Fibrillation: A Combined Affirm and AF-CHF Sub-Study

Cited by 2 publications

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Atrial fibrillation in heart failure: drug therapies for rate and rhythm control

Atrial fibrillation in heart failure: drug therapies for rate and rhythm control

Challenging the status quo: β-blockers for HF plus AF

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