46-Year-Old Man With Fevers, Chills, and Pancytopenia

Kelm, Diana J.; Torres, Katherine Milagros Gómez; Sohail, M. Rizwan

doi:10.1016/j.mayocp.2012.03.012

Cited by 5 publications

(7 citation statements)

References 16 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Sunscreen is advised. 42 Furthermore, HCV-positive patients are at a much higher risk for HCC than most undergoing a liver transplant. 37 While existing HCC should be cured with a liver transplant, recurrence of malignancy is possible.…”

Section: Long-term Carementioning

confidence: 99%

See 1 more Smart Citation

Challenging hepatitis C-infected liver transplant patients

Oliver¹,

Ortiz²,

Ortíz³

2016

HMER

View full text Add to dashboard Cite

Caring for liver transplant patients suffering from chronic hepatitis C virus (HCV) infection is a challenging task for transplant surgeons and primary physicians alike. HCV is the leading cause of liver transplantation in the USA and comes with a myriad of complications that increase morbidity and mortality. This review focuses on patient follow-up, spanning from before the liver transplant occurs to the patient’s long-term health. Pretransplant, both donor and recipient variables, must be carefully chosen to ensure optimal surgical success. Risk factors must be identified and HCV viral load must be reduced to a minimum. In addition to standard transplant complications, HCV patients suffer from additional problems, such as fibrosing cholestatic hepatitis and widespread viremia. Physicians must focus on the balance of immunosuppressive and antiviral medications, while considering possible side effects from these potent drugs. Over the years following surgery, physicians must identify any signs of failing liver health, as HCV-positive patients have an increased risk for cirrhosis and certain life-threatening malignancies.

show abstract

Section: Long-term Carementioning

confidence: 99%

“…Biopsies, imaging, ultrasound, and HCV-polymerase chain reaction testing can help diagnose the cause of hepatic decompensation. 42 …”

Section: Long-term Carementioning

confidence: 99%

Challenging hepatitis C-infected liver transplant patients

Oliver¹,

Ortiz²,

Ortíz³

2016

HMER

View full text Add to dashboard Cite

show abstract

“…Pancytopenia is the reduction in all blood cell lines. A reduced production of the cell lines, intrinsic, or an increased destruction of the cell lines, extrinsic, can cause pancytopenia [1]. Pancytopenia can insidiously develop over a period.…”

Section: Introductionmentioning

confidence: 99%

Trimethoprim-sulfamethoxazole Induced Pancytopenia: A Common Occurrence but A Rare Diagnosis

Parajuli

Ibrahim

Siddiqui

et al. 2019

Cureus

View full text Add to dashboard Cite

Trimethoprim-sulfamethoxazole (TMP-SMX) is a bacteriostatic antimicrobial medication used for the treatment of a variety of infections and has many reported skin and hematologic side effects. Due to the easy availability and cost effectiveness, TMP-SMX is one of the medications commonly used for treatment of skin and soft tissue in patients with methicillin-resistant Staphylococcus aureus (MRSA) infection. One of the rare hematologic manifestations of TMP-SMX is pancytopenia, which is a reduction in all cell lines. In this case report, we are documenting a case of pancytopenia due to severe drug reaction to TMP-SMX in a 70-year-old female after two weeks of medication use. Upon initial stabilization she underwent a thorough workup and was subsequently diagnosed with severe drug-induced pancytopenia. Detailed history, early diagnosis, prompt discontinuation of the offending medication along with supportive care remain the mainstay of treatment in the management of TMP-SMX induced pancytopenia.

show abstract

“…There are three stages of clinical manifestations in Lyme disease 1 3 4 8 9. Stage 1 occurs within weeks after infection and patients often report a ‘flu-like’ illness, lymphadenopathy and the classical erythema migrans (EM) rash, that is, an erythematous patch with a central clearing 1 7 10––12.…”

Section: Introductionmentioning

confidence: 99%

“…Stage 1 occurs within weeks after infection and patients often report a ‘flu-like’ illness, lymphadenopathy and the classical erythema migrans (EM) rash, that is, an erythematous patch with a central clearing 1 7 10––12. Stage 2 occurs within weeks to months after infection and presents with more systemic involvement; patients may experience migratory arthalgias, myalgias, cranial nerve palsies and atrioventricular-node heart block, along with general systems of fatigue, malaise and multiple EM lesions 1 8 9 11 13––15. Stage 3 occurs months to years after infection and classically presents with a recurrent monoarthritis or oligoarthritis of the large joints, polyneuropathy, neurological manifestations and an acrodermatitis chronica atrophicans skin rash 1 8 10 11 13…”

Section: Introductionmentioning

confidence: 99%

Pancytopenia in Lyme disease

Mehrzad

Bravoco

2014

BMJ Case Reports

View full text Add to dashboard Cite

We present a 49-year-old man with subacute onset of fever, weakness, shortness of breath, unilateral lower extremity oedema and pancytopenia who was found to have positive serology for Lyme disease. The patient presented with an intravascular haemolytic pattern on laboratory findings where an extensive infectious disease and haematological workup ruled out ehrlichiosis, anaplasmosis, babesiosis, Rocky Mountain spotted fever, HIV, hepatitis B and other parasitic infections. This left a very atypical presentation of Lyme disease.

show abstract

46-Year-Old Man With Fevers, Chills, and Pancytopenia

Cited by 5 publications

References 16 publications

Challenging hepatitis C-infected liver transplant patients

Challenging hepatitis C-infected liver transplant patients

Trimethoprim-sulfamethoxazole Induced Pancytopenia: A Common Occurrence but A Rare Diagnosis

Pancytopenia in Lyme disease

Contact Info

Product

Resources

About