46. Borazoles. Part II. The preparation of methyl and ethyl derivatives of borazole with the aid of alkyl-lithiums

Nucleophilic Aromatic Substitution Reactions of 1,2‐Dihydro‐1,2‐Azaborine

“…The corresponding substitution reaction with benzene typically requires a stronger nucleophile (e.g., tBuLi) and much harsher conditions (e.g., reflux in decalin at 165 8C for 20 h). [11,12] Having established the optimal reaction conditions for this new substitution reaction, we then sought to expand its substrate scope. As can be seen from Table 2, oxygen-based nucleophiles are suitable for this reaction, including sodium tert-butyloxide (entry 1) and potassium allyloxide (entry 2).…”