Abstract:In the TRIPOD study, troglitazone` treatment of Hispanic women with prior gestational diabetes (GDM) reduced the incidence of type 2 diabetes by 55%, from 12.1% to 5.4% per year in a manner that was closely related to reduction of endogenous insulin requirements effected by amelioration of insulin resistance. Women who completed the TRIPOD study and post-trial drug washout were asked to participate in the Pioglitazone in Prevention of Diabetes (PIPOD) study if their HbA1C was ≤7%. Women were placed on pioglita… Show more
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.