439-P: Microalbuminuria and Hypertension among Indian Patients with Type 2 Diabetes—A Community-Based Cross-Sectional Study

Abstract

Background and Aims: The India Microalbuminuria Survey (IMS) was a cross-sectional, national survey to understand the prevalence of microalbuminuria (MAU) in Indian hypertensive patients. In the IMS study, 992 patients out of 1369 were diabetic. The objectives of this subset analysis were to estimate the prevalence of microalbuminuria in Indian hypertensives patients with concomitant T2DM. Methods: This cross-sectional subset analysis included 992 diabetic patients visiting a physician’s clinic, from 121 centres across India. Inclusion criteria were male and female outpatients aged ≥ 18years with hypertension and concomitant type II DM and no reason for false positive microalbuminuria reflected in dipstick tests. Exclusion criteria were presence of secondary hypertension and existing CKD. Microalbuminuria was diagnosed if the urinary albumin excretion was more than 30 mg/L using the ACR Kit manufactured by Biosense Technologies Pvt. Ltd. Patient data was analyzed with the help of the SPSS software. Results: The mean age of the patients was 54.04 years. There were 186 (18.75 %) patients below 45 years of age and 806 (81.25%) patients more than 45 years of age. The prevalence of microalbuminuria in hypertensive patients with concomitant type II DM was 31.04 %. The prevalence was 34.4% in patients below 45 years of and 30.27% in patients above 45 years age. Conclusions: This study reports a high prevalence of microalbuminuria in Indian patients with hypertension and concomitant type II DM. Hence, early recognition of renal dysfunction through detection of microalbuminuria and to start treatment without any delay will confer future protection from end stage renal disease as well as hypertension and its complications in type 2 diabetic patients. Disclosure B.Saboo: None. K.Mehta: Employee; JB Chemicals and Pharmaceuticals Ltd. A.Naik: Employee; JB Chemicals and Pharmaceuticals Ltd.