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Alkylation of o-cresol by polyprenols

“…The choice of o-cresol was due to the presence of two strong o-and p-orienting groups, i.e., methyl and hydroxyl, through the action of which the prenyl moiety could be directed into the o-and p-positions to form a mixture of polyprenol isomers. Furthermore, the expected compounds could exhibit new biological properties owing to the high biological activity [6].Alkylation of cresol by polyprenols (1) was carried out according to the method developed for alkylation of phenol by geraniol in the presence of aluminum alkoxides [7,8]. The Friedel-Crafts alkylation catalyst was aluminum o-cresolate (2).…”

“…The choice of o-cresol was due to the presence of two strong o-and p-orienting groups, i.e., methyl and hydroxyl, through the action of which the prenyl moiety could be directed into the o-and p-positions to form a mixture of polyprenol isomers. Furthermore, the expected compounds could exhibit new biological properties owing to the high biological activity [6].…”

Polyisoprenoids from leaves of Morus alba and M. nigra

“…In particular, the preparation gamapren (OOO GamaVetFarm, Russia) based on moraprenols is manufactured by phosphorylation of polyprenols isolated from Morus spp. The preparation exhibits antiviral action against Herpes viruses by suppressing the synthesis of viral proteins and stimulating the production of interferons [4].In continuation of research on plant polyprenols [5][6][7][8] and in order to compare the quantitative contents of M. alba and M. nigra polyprenols, we present results from a study of polyisoprenols from these two mulberry varieties growing in Tashkent Oblast.Total polyisoprenoids were isolated by the previously published method [9]. Dried and ground leaves (10 g) produced total polyisoprenoids in 2.6 and 3.2% yields.…”

“…In continuation of research on plant polyprenols [5][6][7][8] and in order to compare the quantitative contents of M. alba and M. nigra polyprenols, we present results from a study of polyisoprenols from these two mulberry varieties growing in Tashkent Oblast.…”

Polyprenols from Althaea armeniaca leaves

“…Our goal was to study polyprenols (PP) of A. armeniaca according to vegetative phase because it is known that PP are biologically active and have low toxicity [3][4][5].…”