42 Social and economic impact of cervical cancer in brazil: analysis of EVA/EVITA cohort study (LACOG 0215)

Abstract

SLN cohort had a median age of 66 years, compared to 68 years in the LND cohort (p>0.05). Median follow-up time was 23 months (range, 1-96) in the SLN cohort and 66 months (range, 4-265) in the LND cohort (p<0.001). In patients with stage I/II disease (n=160, 60.1%), the 2-year OS was 96.6% (SE ±3.4) in the SLN cohort and 89.6% (SE ±2.2) in the LND cohort (p=0.8). In patients with stage III disease (n=77), the 2-year OS was 73.6% (SE ±10.2) in the SLN cohort and 77.3% (SE±5.8) in the LND cohort (p=0.8). Conclusions SLN mapping alone and systematic pelvic and paraaortic nodal dissection (LND) led to similar survival outcomes in patients with stage I-III USC. In our practice, the SLN mapping algorithm has replaced systematic LND as the primary staging modality in the setting of apparent uterineconfined endometrial serous cancer.