410 Allergenicity of the mite, Blomia tropicalis

Fernández-Caldas, Enrique; Fox, Roger W.; Trudeau, Walter L.; Lockey, R.F.

doi:10.1016/0091-6749(88)90644-6

Cited by 6 publications

(4 citation statements)

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“…Preliminary data suggest that Bt is a mite of allergenic importance and that specific IgE to Bt can be detected in mite-allergic individuals in Tampa, FL. 13 Cm was found in 33 samples, generally associated with large colonies of Dp and/or Df The presence of Cm, a predator mite, in house dust may be of clinical importance since these mites have been identified as causing papular urticaria. 34 .…”

Section: Discussionmentioning

confidence: 97%

House Dust Mite Allergy in Florida. Mite Survey in Households of Mite-Sensitive Individuals in Tampa, Florida

Fernández-Caldas

Fox²,

Bucholtz³

et al. 1990

allergy asthma proc

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This study evaluated the prevalence of positive house dust mite skin tests in a population of atopic individuals and identified the mite species present in mattress and house dust samples in homes of the Tampa Bay area. Four hundred consecutive individuals were evaluated for respiratory complaints and skin tested with standardized extracts of Dermatophagoides pteronyssinus (Dp) and Dermatophagoides farinae (Df). Two hundredforty individuals (60%) had a positive skin test to the mite extracts. Dust samples were collected in 40 homes of mite-allergic individuals and analyzed by light microscopy. Mite species were found in 53 of the 60 dust samples (20 mattresses and 40 carpets). Mite numbers ranged from 110-6200 miteslg of mattress dust andfrom 120-5500 miteslg of carpet dust. Eleven different mite species were identified and Blomia tropicalis (Bt), not previously identified in the United States, was found in 30% of the samples. Dp and Df were the predominant species. These observations suggest that house dust mite allergy is common in the Tampa Bay area and that the house dust mitefauna comprises several mite species besides Dp and Of. Prospective studies in progress are designed to confirm the role of different mite species in house dust mite allergy.

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Section: Discussionmentioning

confidence: 97%

House Dust Mite Allergy in Florida. Mite Survey in Households of Mite-Sensitive Individuals in Tampa, Florida

Fernández-Caldas

Fox²,

Bucholtz³

et al. 1990

allergy asthma proc

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“…Based on these studies, there is minimal-to-moderate cross-reactivity between B. tropicalis and Dermatophagoides spp. The lack of studies using internationally standardized B. tropicalis extracts hampers, to a certain extent, the complete understanding and full analysis of these results [100,101]. The same concept is true for the rest of the mite extracts that have been used in population-based studies to establish sensitization rates.…”

Section: Clinical Significance Of Sensitization To Domestic Mitesmentioning

confidence: 96%

Mite allergens

Fernández-Caldas¹,

Calvo²

2005

Curr Allergy Asthma Rep

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There is an increasing awareness of the health implications of mite sensitivity, as it is closely related to asthma. Mite allergy constitutes a complex worldwide problem, with sanitary and economical implications. Not only are mite species present in house dust, producing potent allergens, but other, less studied species are also responsible for significant allergic reactions in occupational settings. In this review, we focus on the growing number of mite species that are implicated in allergic cutaneous and respiratory diseases in humans. Mite allergy is not restricted only to the human "indoor" environment, because numerous reports clearly demonstrate that many species that can induce sensitization and symptoms are encountered in occupational settings. An important component of allergy research is the evaluation of the allergenic cross-reactivity to verify to what extent different mite species have unique, species-specific, or cross-reactive allergens. The results of these investigations have important clinical consequences for the diagnosis and treatment of allergic diseases. Internationally standardized mite extracts are needed to compare sensitization rates around the world and clearly establish risk factors associated with sensitization and asthma. In spite of recent controversial results, a significant reduction in the exposure to mite allergens continues to be an important challenge and one of the main goals in the treatment of mite-induced respiratory symptoms. In many cases, this reduction must be achieved in the workplace as well as in the home environment.

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“…It has been well established that mite species such as Dermatophagoides pteronyssinus, Dermatophagoides farinae and Euroglyphus maynei from the family Pyroglyphidae are important clinical species (1–4). In recent years, Blomia tropicalis mite classified under the family Glycyphagidae (5) is an important source of indoor allergens that associate with allergic asthma and rhinitis in the tropics (6–11). The first major B. tropicalis allergen cloned was Blo t 5 (12, 13).…”

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confidence: 99%