“…One of the three compounds with structures related to strychnine (Figure 1), 3[dimethyl-aminomethyl]indole (gramine) was obtained from Aldrich. The other two were synthesized as follows: 3-methylindole,2-butyrolactam, by acid catalysed rearrangement of the monophenylhydrazone of 2methyl,1,3-cylcohexanedione (Merling, 1894;Teuber et al, 1964) and 3-methyoxy-methyl-indole from gramine methiodide by methoxide substitution (Jacob & Madinaveitia, 1937;Schram, 1951).…”