Abstract:Study Objectives: Medical comorbidities, including diabetes mellitus, hypertension, congestive heart failure, ischemic heart disease, malignancy, end-stage renal disease (ESRD), and chronic obstructive pulmonary disease (COPD) are known to influence the body's immune response to infection. However, the effect of patient comorbidities on the development of sepsis and mortality rates for "pre-shock" septic patients are not well understood.Methods: We performed a retrospective review of consecutive adult (>18 yea… Show more
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