4-Phenyl-1,2,4-triazaspiro[4.6]undec-1-ene-3-thione

Abstract

In the title compound, C14H17N3S, the plane of the phenyl ring makes a dihedral angle of 74.90 (4)° with that of the tri­aza­thione ring (r.m.s. deviation = 0.001 Å), while the seven-membered ring adopts a twist-chair conformation. No specific intermolecular interactions are discerned in the crystal packing.

1-[(Cyclohexylidene)amino]-3-(prop-2-en-1-yl)thiourea

“…For the use of thiosemicarbazides as intermediates in the synthesis of different heterocyclic compounds, see: ; Mohamed et al (2014); Akkurt et al (2014a). For the bioactivity of thiosemicarbazones, see: Bahat et al (2006); Qandil et al (2006); Singh et al (2001;Kalyoncuog lu et al (1992) Bahadur & Goel (1976).…”

“…It is well known that thiosemicarbazides are the key intermediates used in the synthesis of many heterocyclic compounds such as thiazolidinones (Mague et al, 2014), triazols (Mohamed et al, 2014) and thiazoles (Akkurt et al, 2014a). Thiosemicarbazone derivatives have displayed various pharmacological properties such as analgesic (Bahat et al, 2006), antibacterial (Qandil et al, 2006), anti-fungal, anti-tumoral (Singh et al, 2001;Kalyoncuoğlu et al, 1992) and antitubercular (Bahadur & Goel, 1976) activities.…”