4-Hydroxy-5-methylcoumarin derivatives from Diospyros kaki Thunb and D. kaki var. Sylvestris makino; structure and synthesis of 11-methylgerberinol

Paknikar, S. K.; Fondekar, Kamlesh Pai; Kirtany, J. K.; Natori, Shinsaku

doi:10.1016/0031-9422(95)00698-2

Cited by 18 publications

(9 citation statements)

References 1 publication

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The 13 C NMR showed 23 carbon signals, and DEPT spectrum analysis showed 11 signals as singlets, 10 signals as doublets, and two signals as quartets. Two methoxyl groups were assigned to positions of C-7 and C-7‘, as expected from the biogenetic pathways, and it was confirmed by a NOESY experiment. Based on the above information, the partial structures for 1 could be proposed as shown in Figure A.…”

Section: Resultssupporting

confidence: 61%

Coumarins from the Fruits of Cnidium monnieri

et al. 2000

View full text Add to dashboard Cite

Two novel biscoumarins, cnidimonal (1) and cnidimarin (2), and two new coumarin derivatives, 5-formylxanthotoxol (3) and 2'-deoxymeranzin hydrate (4), were isolated from a traditional Chinese crude drug, the fruits of Cnidium monnieri, together with 15 known compounds. Among the known compounds, five of the minor compounds were isolated for the first time from this plant. The structures of 1-4 were determined with the use of spectroscopic methods.

show abstract

Section: Resultssupporting

confidence: 61%

Coumarins from the Fruits of Cnidium monnieri

et al. 2000

View full text Add to dashboard Cite

show abstract

“…Even though numerous studies have analyzed phytochemicals and their biological activities in persimmons (12,15,16, 29), the exact phenolic compounds have still not been fully characterized. For these first attempts at a metabolomics approach of phenolic compounds in persimmon fruit juice, we elucidated nine phenolic acids and seven catechins (Fig.…”

Section: Resultsmentioning

confidence: 99%

“…Persimmon fruits are renowned as phenolic compound and carotenoid-rich sources ( 15 ) that have been widely used as important remedies because of potential beneficial effects on various chronic diseases ( 16 ). Even though numerous studies have analyzed phytochemicals and their biological activities in persimmons ( 12 , 15 , 16 , 29 ), the exact phenolic compounds have still not been fully characterized. For these first attempts at a metabolomics approach of phenolic compounds in persimmon fruit juice, we elucidated nine phenolic acids and seven catechins ( Fig.…”

Section: Resultsmentioning

confidence: 99%

Comparative Studies of Antioxidant Activities and Nutritional Constituents of Persimmon Juice (Diospyros kaki L. cv. Gapjubaekmok)

Lee¹,

Lee²,

Seo³

et al. 2012

JFN

View full text Add to dashboard Cite

The objectives of this research were to evaluate antioxidant activities and nutritional components, including phenolic acid, catechin, organic acid, sugar, and amino acid, of persimmon juice from persimmons grown in different regions around Korea. Persimmon (Diospyros kaki) exhibits potent antioxidant effects in DPPH, ABTS, reducing power, and FRAP methods of analysis. The levels of nutritional constituents showed significant differences among all the samples. In particular, tartaric acid, glucose, gallic acid, epicatechin gallate and aspartic acid were observed to be the predominant component for each of their general chemical groups, with total average contents of 1876.51 mg/kg, 62.69 g/kg, 12.73 mg/kg, 208.99 mg/kg, and 31.84 mg/100 g, respectively. Interestingly, persimmons from the Hadong region presented the highest sugar (130.60 g/kg), phenolic acid (42.27 mg/kg), and catechin (527.97 mg/kg) contents in comparison with other regional samples. Moreover, this location exhibited the greatest antioxidant activity with highest total phenolic (298.01 mg GAE/kg) and flavonoid (32.11 mg/kg RE) contents. Our results suggest that strong antioxidant activities of persimmons correlate with high phenolic acid and catechin contents, particularly gallic acid and epicatechin gallate. Additionally, these two compounds may be key factors when considering the useful ingredients of persimmon.

show abstract

“…arenarium 23 , kunzeagin A (a dimeric flavonol glycoside) from Kunzea ambigua 24 , gerberinol from Diospyros kaki var. sylvestris 25 , and four acylphloroglucinol derivatives from Hypericum andinum 26 . As far as we know, very few of these natural dimers was identified in microbial kingdom, that is phaeochromycins F from Streptomyces sp.…”

Section: Discussionmentioning

confidence: 99%

New α-glucosidase inhibitors from marine algae-derived Streptomyces sp. OUCMDZ-3434

Chen

Hao

Wang

et al. 2016

Sci Rep

View full text Add to dashboard Cite

Wailupemycins H (1) and I (2) with a new skeleton coupled two 6-(2-phenylnaphthalene-1-yl)pyrane-2-one nuclei to a –CH2– linkage were identified from the culture of Streptomyces sp. OUCMDZ-3434 associated with the marine algae, Enteromorpha prolifera. Compounds 1 and 2 are two new α-glucosidase inhibitors with the Ki/IC50 values of 16.8/19.7 and 6.0/8.3 μM, respectively. In addition, the absolute configurations of wailupemycins D (3) and E (4) are also resolved in this paper for the first time.

show abstract

4-Hydroxy-5-methylcoumarin derivatives from Diospyros kaki Thunb and D. kaki var. Sylvestris makino; structure and synthesis of 11-methylgerberinol

Cited by 18 publications

References 1 publication

Coumarins from the Fruits of Cnidium monnieri

Coumarins from the Fruits of Cnidium monnieri

Comparative Studies of Antioxidant Activities and Nutritional Constituents of Persimmon Juice (Diospyros kaki L. cv. Gapjubaekmok)

New α-glucosidase inhibitors from marine algae-derived Streptomyces sp. OUCMDZ-3434

Contact Info

Product

Resources

About