4‐Functionally‐Substituted 3‐Heterylpyrazoles. Part 15. 3‐Aryl(heteryl)‐1‐phenyl‐4‐pyrazolylmethylamines and Heterocumulenes Obtained Therefrom.

Abstract

Pyrazole derivatives R 01804-Functionally-Substituted 3-Heterylpyrazoles. Part 15. 3-Aryl(heteryl)-1-phenyl-4-pyrazolylmethylamines and Heterocumulenes Obtained Therefrom. -Pyrazolylmethylamines (IV) are prepared in good yields by a convenient two-step procedure via Gabriel reaction followed by hydrazinolysis of the phthalimides (III). The reaction of amines (IV) with triphosgene leads to the isocyanates (VI), while the reaction with CS 2 affords isothiocyanates (VIII) in a pure state. -(BRATENKO, M. K.; PANIMARCHUK, O. I.; MEL'NICHENKO, N. V.; VOVK, M. V.; Russ. J. Org. Chem. 41 (2005) 2, 238-242; Bukovina State Med. Acad., Chernovtsy 58000, Ukraine; Eng.) -R. Staver 39-113