4-Bromo-N-cyclohexylbenzenesulfonamide

Abstract

The title compound, C12H16BrNO2S, adopts an L-shaped conformation with the central C—S—N—C torsion angle being −77.8 (3)°. The crystal packing features N—H⋯O hydrogen bonds, which lead to C(4) chains propagating in [010]; the second O atom is involved in short intra­molecular C—H⋯O contacts.

4-Chloro-N-cyclohexylbenzenesulfonamide

“…Sulfonamide group containing drugs are extensively used for the treatment of certain infections caused by Gram-positive and Gram-negative microorganisms (Korolkovas, 1988;Mandell & Sande, 1992). In continuation of our on going structural studies of cyclohexylamine and sulfonamides synthesis (John et al, 2010;Khan et al, 2010;Sharif et al, 2011), herein the crystal structure of title compound (I) is described.…”

“…For background to the pharmacological uses of sulfonamides, see: Korolkovas (1988); Mandell & Sande (1992). For related structures, see: Sharif et al (2011); Khan et al (2010); John et al (2010). For ring conformational analysis, see: Cremer & Pople (1975).…”