4,5-Diaza-9-fluorenone Isonicotinoylhydrazone Monohydrate

Abstract

The title compound, CITHlIN50.HzO, forms twodimensional layers parallel to the (10i) plane. The dihedral angle between the planes of the diazafluorene moiety and the pyridine ring is 27

4,5-Diazafluoren-9-one benzoylhydrazone monohydrate

“…The bond lengths and angles observed in this structure are normal and comparable with those found in the structures of other benzoylhydrazine (Fun et al, 1997) and 4,5-diazauorene derivatives (Lu et al, 1996). The molecule is in the keto tautomeric form.…”

4,5-Diazafluoren-9-ol

“…The bond lengths and angles observed in the structure of (I) are in the normal ranges and are comparable with those found in the structures of other 4,5-diaza¯uorene derivatives (Lu et al, 1995(Lu et al, , 1996. We have reported previously that there is a difference in the behaviour of the two pyridyl N atoms of the diaza¯uorene moiety, in that one can form strong hydrogen bonds and the other cannot (Fun et al, 1995;Shanmuga Sundara Raj et al, 1999).…”

Chains or rings? Polymorphism of an isoniazid derivative derivatized with diacetone alcohol

“…9,10 These interactions can be reduced by changing the primary amine to either a secondary amine or to an imine. [11][12][13][14][15][16][17] This effectively could leave the amide group as the only strong hydrogen bond donor, and thus could possibly allow one to design co-crystals with more robust intermolecular interactions involving the pyridine ring. 18 These hydrazine derivatives of isoniazid also tend to be polymorphic.…”