4′,5,6,7-Tetramethoxyflavone fromMarrubium peregrinum

Salei, L. A.; Popa, D. P.; Lazur'evskii, G. V.

doi:10.1007/bf00636017

Cited by 4 publications

(8 citation statements)

References 3 publications

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“…Ballotetroside (70) was isolated from the water extract. Although all these compounds were already previously isolated from Lamiaceae, only 5,6,7,40-tetramethoxyflavone (63), marrubiin (9) and acteoside (12) were previously reported in M. peregrinum [56].…”

Section: Marrubium Peregrinum Lmentioning

confidence: 97%

“…The essential oil of M. peregrinum revealed the presence ofphellandrene, epi-bicyclosesquiphellandrene and bicyclogermacrene as the major compounds in a sample collected in Greece, while a sample from Central Europe was rich in -caryophyllene and its oxide, bicyclogermacrene and germacrene D [56,57].…”

Section: Marrubium Peregrinum Lmentioning

confidence: 98%

“…Phenolic compounds are predominant in this species, such as flavone aglycones, flavone glycosides, coumaroylated flavone glycosides and acteoside-related phenylethanoids. The following compounds are described: four diterpenoids: peregrinine (40), peregrinol (19), marrubiin (9) and premarrubiin (62) [51,52] and six phenolic compounds: 4',5,6,7-tetramethoxyflavone (63) [53], apigenin (4), kaempferol (64), apigenin-7-O-glucoside (5), luteolin-7-O-glucoside (24) and acteoside (12) [54,55].…”

Section: Marrubium Peregrinum Lmentioning

confidence: 99%

“…The phytochemical composition of the flowering aerial parts of M. peregrinum reveled the isolation of six compounds from the dichloromethane extract, identified as ladanein (65), 6-hydroxy-5,7,4'-trimethoxyflavone (66), 5,6,7,40-tetramethoxyflavone (63), marrubiin (9) and a mixture of the isomers cyllenin A (20) and 15-epi-cyllenin A (21) [55][56][57]. From the aerial parts of the methanol extract, a further five compounds were isolated, identified as acteoside (12), forsythoside B (67), arenarioside (68) and terniflorine (apigenin-7-O-[600-E-p-coumaroyl] -D-glucopyranoside) (69).…”

Section: Marrubium Peregrinum Lmentioning

confidence: 99%

“…The triterpenes oleanolic (56) and ursolic acid (57) are common constituents present in the Lamiaceae family. There is insufficient information available concerning the distribution of these in Lamiaceae, as quantitative investigations generally extend to only a few species.…”

Section: Marrubium Incantum Desrmentioning

confidence: 99%

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A Review of the Chemical and Pharmacological Aspects of the Genus Marrubium

Meyre‐Silva¹,

Cechinel‐Filho

2010

CPD

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The genus Marrubium (Lamiaceae) is comprised of about forty species, distributed in Europe, Asia and Brazil. Some species are traditionally used to treat various diseases, including asthma, pulmonary infections, inflammation and hypotension, as cholagogues and sedative agents, and for pain relief. A literature review on the chemical and biological aspects of these plants indicates antimicrobial activity against gram positive bacteria, analgesic properties, and anti-hypertensive, antidiabetic, antioxidant properties, among others, particularly related to the presence of diterpenes, sterols, phenylpropanoids and flavonoids. This review shows the main chemical and pharmacological aspects of the genus Marrubium, with emphasis on M. vulgare, which grows in Brazil and has been studied by us and other authors.

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Section: Marrubium Peregrinum Lmentioning

confidence: 97%

Section: Marrubium Peregrinum Lmentioning

confidence: 98%