4-[(2,5-Dimethylanilino)acetyl]-3,4-dihydroquinoxalin-2(1H)-one

Abstract

Key indicators: single-crystal X-ray study; T = 296 K; mean (C-C) = 0.003 Å; R factor = 0.048; wR factor = 0.140; data-to-parameter ratio = 17.6.In the title compound, C 18 H 19 N 3 O 2 , the dihedral angle between the benzene rings is 20.47 (10) and an intramolecular N-HÁ Á ÁO hydrogen bond occurs, generating an S(5) ring. In the crystal, inversion dimers linked by pairs of N-HÁ Á ÁO hydrogen bonds lead to R 2 2 (8) loops. Related literature ExperimentalCrystal data

4-[2-(Benzylsulfanyl)acetyl]-3,4-dihydroquinoxalin-2(1H)-one

“…The title compound (I) is in continuation of previously published work on the analoguous structure, 4-[(2,5-dimethylanilino)acetyl]-3,4-dihydroquinoxalin-2(1H)-one (II) (Nasir, et al, 2009). The dihedral angle between the aromatic ring (C1/C2/C3/C4/C5/C6) and pyrazinone (C1/C6/N2/C8/C7/N1)is 14.01 12…”

“…For the biological activity of quinoxalines, see: Ali et al (2000); Moustafa & Yameda (2001). For related structures see: Nasir et al (2009). For graph-set notation, see: Bernstein et al (1995).…”