3β-Hydroxyhexanordammaran-20-one from Euphorbia supina

Sesqui- and triterpenoids from the liverwort Lepidozia chordulifera inhibitors of bacterial biofilm and elastase activity of human pathogenic bacteria

“…In Table 1, our comparative values of diagnostic signals for compounds 3, 4, and 5 in CDCl 3 are presented. Compounds 6, 7, 8, 9, and 10 were identified as the dammaranes shoreic acid (Govindachari et al, 1994), eichlerialactone (Singh and Aalbersberg, 1992), cabraleone, cabraleadiol (Hisham et al, 1996), and 3ß-hydroxynordammaran-20-one (Tanaka et al, 1987) based on their spectroscopic features and by comparison with literature data. Comparative 1 H NMR data for dammaranes 6-9 are presented in Table 2.…”

Supinaionosides A and B: Megastigmane Glucosides and Supinanitrilosides A-F: Hydroxynitrile Glucosides from the Whole Plants of Euphorbia supina RAFINESQUE

“…) to yield 7.0 mg of 6 from the peak at 15 min, 12.8 mg of 9 from the peak at 10 min, and 13.2 mg of 1 and 6.4 mg of 2 from the peaks at 13 min and 16 min, respectively. The residue (25.9 g in fractions 9-13) of the 40-60% MeOH eluate obtained on HP-20 CC was subjected to silica gel (500 g) CC with increasing amounts of MeOH in CHCl 3 Sugar Analysis About 500 mg of each compound, except for 1, was hydrolyzed with 1 N HCl (0.1 ml) at 100°C for 2 h. The reaction mixtures were partitioned with an equal amount of EtOAc (0.1 ml), and the water layers were analyzed with a chiral detector (JASCO OR-2090plus) on an amino column [Asahipak NH2P-50 4E, CH 3 CN-H 2 O (4 : 1), 1 ml/min]. All hydrolyzates gave a peak for D-glucose at 13.7 min with a positive optical rotation sign.…”