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Abstract

The transdermal route of drug delivery has attracted researchers due to many biomedical advantages associated with it. However, excellent impervious nature of skin is the greatest challenge that has to be overcome for successfully delivering drug molecules to the systemic circulation by this route. This review describes enhancement techniques based on drug/vehicle optimization such as physical and chemical penetration enhancers. Various novel carriers and vehicles like micro/nano and multiple emulsion, Liposomes, Niosomes, and Transferosomes etc., along with formulation strategies has also been discussed in the present review.