3PC-030 Analytical method validation to carry out physicochemical stability studies of methadone oral solutions

Abstract

observed in particle size after 60 days in all samples. The organoleptic characteristics (smell, taste and texture) remained unchanged in all of the preparations until the third month. Conclusion and relevance A stable alcohol free diazepam suspension was achieved. The tablets produced a more stable formulation than the bulk source, especially when stored at a lower temperature. This formulation can solve the problem of shortages, allowing the appropriate administration of paediatric treatments, while allowing compliance with the recommended composition limits of ethanol, by excluding this excipient from its composition. REFERENCES AND/OR ACKNOWLEDGEMENTS No conflict of interest.