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Abstract

Aim: Comparative analysis of the impact of artificially and naturally ripened fruit on obesity-induced biochemical and hematological alterations was carried out.Methodology: 4 g/kg of monosodium glutamate (MSG) was injected on neonates on day 2, 4, 6, 8, 10 to induced experimental obesity. 25g/kg of calcium carbide, CaC 2 was used to artificially ripen fruits and naturally ripened fruit was also prepared. At age 7 months, Wistar rats induced with obesity were treated with artificially and naturally ripened fruits in their various groups for 28 days. Biochemical and hematological parameters related to oxidative stress, liver, kidney and blood functions were assayed.Results: MSG-induced obesity significantly altered the bio-chemicals (MDA, SOD, CAT, GPx, AST, ALT, GGT, ALP, Urea, Creatine, K + , Na + , Cl -) and hematological parameters (RBC, PCV, Hb, WBC, WBC differential count) suggesting obesity could predispose to oxidative stress, liver, kidney and blood dysfunction; furthermore, naturally ripened fruit was able to significantly mitigate the effects exerted by obesity while artificially ripened enhanced the effects. Conclusion:Fruit could be beneficial for obesity-induced biochemical and hematological alterations, but artificially ripened fruits could be deleterious to the stated condition. Hence, measures needs to be taken to ensure naturally ripened fruits are consumed since it can be beneficial to obesity-induced biochemical and hematological alterations as observed in this study.