Abstract:Objective: The present study aimed to develop sustained released 5-fluorouracil loaded chitosan-pectin blended dual cross-linked gel beads system. Materials and Methods: Dual cross-linked beads were evaluated for drug content, particle size, swelling degree, scanning elecron microscopy, differential scanning calorimetry, X-ray diffraction, etc., for its suitability for colon targeting. Results: The developed systems were appreciably performed during in vitro drug releases in simulated gastric (simulated gastri… Show more
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