3D ultrashort echo time MRI of the lung using stack‐of‐spirals and spherical <i>k</i>‐Space coverages: Evaluation in healthy volunteers and parenchymal diseases

Dournes, Gaël; Yazbek, Joseph; Benhassen, Wadie; Benlala, Ilyes; Blanchard, Élodie; Truchetet, Marie-Élise; Macey, Julie; Berger, Patrick; Laurent, François

doi:10.1002/jmri.26212

Cited by 39 publications

(38 citation statements)

References 31 publications

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“…A retrospective gating was nevertheless performed; therefore, with an undersampling degree higher than that used for the VIBE, UTE-HF-NIV, and UTE-Avg methods. Therefore, further studies are required to assess the advantage of HF-NIV when compared with gated acquisitions 2,17,23,25,27,32,33 or motionresolved reconstructions 26 at an equivalent sampling level. While the VIBE acquisition provided a valuable point of reference as a sequence frequently used in clinical practice, further comparisons with optimized breath-hold protocols [34][35][36] could be of value.…”

Section: Discussionmentioning

confidence: 99%

Ultrashort echo time imaging of the lungs under high‐frequency noninvasive ventilation: A new approach to lung imaging

Delacoste

Dournes

Dunet

et al. 2019

Magnetic Resonance Imaging

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BackgroundAlthough ultrashort echo time (UTE) sequences allow excellent assessment of lung parenchyma, image quality remains lower than that of computed tomography (CT).PurposeTo investigate a high‐frequency noninvasive ventilation (HF‐NIV) technique allowing a stabilized inspiration and to compare image quality with current dedicated MR sequences.Study TypeProspective.PopulationTen healthy volunteers.Field Strength/Sequence3D radial UTE sequence at 1.5T.AssessmentUTE‐HF‐NIV sequence was compared with UTE‐free‐breathing (UTE‐FB), reconstructed at end expiration (UTE‐Exp) and average (UTE‐Avg), and breath‐hold VIBE sequences. The distance from lung apex to the dome of the right hemidiaphragm was measured. Visual assessment of the visibility and sharpness of normal anatomical structures was carried out. Dedicated software also quantitatively evaluated vessel–lung and right lung–liver interface sharpness. Apparent signal ratio (Sr) and contrast ratios (Cr) were quantitatively evaluated.Statistical TestsWilcoxon signed rank test for visual scores, paired t‐test for continuous variables, significance at P < 0.05.ResultsThe distance between apex and the right hemidiaphragmatic dome was significantly larger (P < 0.001) with UTE‐HF‐NIV compared with UTE‐FB and VIBE acquisitions. Vessel and airway visibility had identical median visual scores with all UTE methods. Median visual scores for sharpness of vessels and airways were significantly higher (P < 0.001) with HF‐NIV (vessels = 3; airways = 2) than in UTE‐FB (vessels = 2; airways = 1) and VIBE (vessels = 1; airways = 1). Software‐based vessel sharpness evaluation resulted in larger values in 8/10 volunteers with UTE‐HF‐NIV (67.3 ± 9.8) compared with UTE‐Avg (62.3 ± 12.6) but the average difference was not significant (P = 0.28). The sharpness of the lung–liver interface was significantly higher (P < 0.001) with HF‐NIV (17.3 ± 5.3) compared with UTE‐Avg (14.1 ± 3.9). Significantly higher values (P < 0.01) of Sr and Cr were observed with UTE‐HF‐NIV compared with UTE‐FB and VIBE.Data ConclusionHF‐NIV allowing acquisition at full inspiration significantly improves image quality for lung imaging. This could offer the option to alternate some follow‐up CT studies by using this technique. Level of Evidence: 2 Technical Efficacy: Stage 1J. Magn. Reson. Imaging 2019;50:1789–1797.

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Section: Discussionmentioning

confidence: 99%

Ultrashort echo time imaging of the lungs under high‐frequency noninvasive ventilation: A new approach to lung imaging

Delacoste

Dournes

Dunet

et al. 2019

Magnetic Resonance Imaging

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“…Dournes et al 38 produced submillimeter imaging of the lung using pointwise encoding time reduction with radial acquisition (PETRA), and this has also been assessed against a UTE sequence in the lung. 39 Nazaran et al 40 utilized T2* UTE mapping in the lung. Delacoste et al 41 performed UTE imaging with advanced reconstruction on cystic fibrosis patients.…”

Section: Clinical Motivationmentioning

confidence: 99%

“…As examples, Herrmann et al optimized a three‐dimensional (3D) UTE sequence both shortening the repetition time and providing automatic gradient delay compensation. Dournes et al produced submillimeter imaging of the lung using pointwise encoding time reduction with radial acquisition (PETRA), and this has also been assessed against a UTE sequence in the lung . Nazaran et al utilized T2* UTE mapping in the lung.…”

Section: Clinical Motivationmentioning

confidence: 99%

PET/MRI attenuation estimation in the lung: A review of past, present, and potential techniques

et al. 2020

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Positron emission tomography/magnetic resonance imaging (PET/MRI) potentially offers several advantages over positron emission tomography/computed tomography (PET/CT), for example, no CT radiation dose and soft tissue images from MR acquired at the same time as the PET. However, obtaining accurate linear attenuation correction (LAC) factors for the lung remains difficult in PET/MRI. LACs depend on electron density and in the lung, these vary significantly both within an individual and from person to person. Current commercial practice is to use a single‐valued population‐based lung LAC, and better estimation is needed to improve quantification. Given the under‐appreciation of lung attenuation estimation as an issue, the inaccuracy of PET quantification due to the use of single‐valued lung LACs, the unique challenges of lung estimation, and the emerging status of PET/MRI scanners in lung disease, a review is timely. This paper highlights past and present methods, categorizing them into segmentation, atlas/mapping, and emission‐based schemes. Potential strategies for future developments are also presented.

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“…However, CT has been previously validated versus pathologic examination (33). Fifth, we used only pointwise encoding time reduction with radial acquisition for 3D UTE MRI (34). Therefore, the threshold of 0.20 to calculate percentage of low-signal-intensity volume cannot be thought of as generalizable.…”

Section: Supportive Evaluations Of Mri Validitymentioning

confidence: 99%

Automated Volumetric Quantification of Emphysema Severity by Using Ultrashort Echo Time MRI: Validation in Participants with Chronic Obstructive Pulmonary Disease

Benlala¹,

Berger²,

Girodet³

et al. 2019

Radiology

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hronic obstructive pulmonary disease (COPD) is characterized by persistent respiratory symptoms and airflow limitation (1) and is the third leading cause of mortality worldwide (2). In the past decades, chest CT has helped to provide valuable insights into COPD. Indeed, CT enables noninvasive, in vivo, and three-dimensional (3D) quantification of the key components of the disease, such as bronchial remodeling (3) and emphysema (4). Evidence of COPD subtypes (1), relationship with genetic variants (5), longitudinal follow-up (6), and mortality (7) have been investigated at CT. More recently, in an era where the advent of artificial intelligence may allow intricate combinations of both morphologic and functional information, lung MRI has emerged as a radiation-free modality for the longitudinal follow-up of lung diseases and (8) to help better identify participant phenotype or predict disease outcomes (9). Studies related to ventilation (10), perfusion (11), dynamic biomarkers (12), and coupling between the cardiovascular and pulmonary systems (13,14) at MRI have been performed. However, there are few studies that evaluated the regional extent of emphysema by using MRI (15-18). Recent advances with ultrashort echo times (UTEs) have been shown to enable submillimeter resolution with good contrast in three dimensions (19,20).

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3D ultrashort echo time MRI of the lung using stack‐of‐spirals and spherical k‐Space coverages: Evaluation in healthy volunteers and parenchymal diseases

Abstract: 2 Technical Efficacy: Stage 1 J. Magn. Reson. Imaging 2018;48:1489-1497.

Cited by 39 publications

References 31 publications

Ultrashort echo time imaging of the lungs under high‐frequency noninvasive ventilation: A new approach to lung imaging

Ultrashort echo time imaging of the lungs under high‐frequency noninvasive ventilation: A new approach to lung imaging

PET/MRI attenuation estimation in the lung: A review of past, present, and potential techniques

Automated Volumetric Quantification of Emphysema Severity by Using Ultrashort Echo Time MRI: Validation in Participants with Chronic Obstructive Pulmonary Disease

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