3D Slicer

Pieper, Steven; Halle, Morris; Kikinis, Ron

doi:10.1109/isbi.2004.1398617

Cited by 350 publications

(245 citation statements)

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“…Computed tomographic scans were segmented using Slicer 3D software (Pieper et al, 2004) to delineate radius, ulna, and humerus, cortical, trabecular bone and cartilage of the area of interest. Based on these structure identifications, a three-dimensional model of the canine elbow was constructed using an automatic procedure described in (D'Otreppe et al, 2010;D'Otreppe et al, 2012).…”

Section: Finite Element Analysismentioning

confidence: 99%

Intraosseous stress distribution and bone interaction during load application across the canine elbow joint: A preliminary finite element analysis for determination of condylar fracture pathogenesis in immature and mature dogs

Böhme

D'Otreppe

Ponthot

et al. 2016

Research in Veterinary Science

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Distal humeral fractures are common fractures especially in immature small breed dogs. The pathogenesis is still unknown. For this study, a three-dimensional bone model of the canine elbow was created and finite element analysis performed in order to determine the relationship between fracture type and bone interactions. Fused and non-fused humeral condyles were considered. A failure criterion was implemented to simulate the pathogenesis until fracture. Our study results confirm the clinical observation that lateral condylar fracture is the most common fracture type, implying interaction with the radius. Medial and Y-fractures are less common and occur always in interaction with the ulna whereas the radius causes lateral condylar fracture. Additionally, the fracture type is sensitive to bone positioning during trauma. The pathogenesis of distal humeral fractures is more complex than generally reported in the literature.

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Section: Finite Element Analysismentioning

confidence: 99%

Intraosseous stress distribution and bone interaction during load application across the canine elbow joint: A preliminary finite element analysis for determination of condylar fracture pathogenesis in immature and mature dogs

Böhme

D'Otreppe

Ponthot

et al. 2016

Research in Veterinary Science

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“…All tumor segmentations were done using 3D Slicer software, version 4.1 (Brigham and Women's Hospital, Boston, Mass) 22,23 by an investigator (R.R.) who was blinded to clinical outcomes.…”

Section: Tumor Segmentation and Volume Estimationmentioning

confidence: 99%

Recurrent glioblastoma: Volumetric assessment and stratification of patient survival with early posttreatment magnetic resonance imaging in patients treated with bevacizumab

Huang

Rahman

Hamdan

et al. 2013

Cancer

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BACKGROUND: Despite a high radiographic response rate in patients with recurrent glioblastoma following bevacizumab therapy, survival benefit has been relatively modest. We assess whether tumor volume measurements based on baseline and early posttreatment MRI can stratify patients in terms of progression-free survival (PFS) and overall survival (OS). METHODS: Baseline (24 1/-4 days) and posttreatment (30 1/-6 days) MRI exams of 91 patients with recurrent glioblastoma treated with bevacizumab were retrospectively evaluated for volume of enhancing tumor as well as volume of the T2/FLAIR hyperintensity. Overall survival (OS) and progression-free survival (PFS) were assessed using volume parameters in a Cox regression model adjusted for significant clinical parameters. RESULTS: In univariable analysis, residual tumor volume, percentage change in tumor volume, steroid change from baseline to posttreatment scan, and number of recurrences were associated with both OS and PFS. With dichotomization by sample median of 52% change of enhancing volume can stratify OS (52 weeks vs. 31 weeks, P 5.013) and PFS (21 weeks vs. 12 weeks, P 5.009). Residual enhancing volume, dichotomized by sample median of 7.8 cm 3 , can also stratify for OS (64 weeks vs. 28 weeks, P <.001) and PFS (21 weeks vs. 12 weeks, P 5.036). CONCLUSIONS: Volumetric percentage change and absolute early posttreatment volume of enhancing tumor can stratify survival for patients with recurrent glioblastoma receiving bevacizumab therapy. Cancer 2013;119:3479-88.

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“…The total intracranial volume was then calculated as the sum of the GM, WM, and CSF volumes. Ventricular CSF volume was quantified by using the 3D Slicer software 17 (version 3.6, http:// www.slicer.org). The ventricular regions, including the lateral, third, and fourth ventricles, and the cerebral aqueduct were segmented on the same T1-weighted volume.…”

Section: Mr Imaging Scan Protocol and Data Analysismentioning

confidence: 99%

MRI Evidence of Impaired CSF Homeostasis in Obesity-Associated Idiopathic Intracranial Hypertension

Alperin¹,

Ranganathan²,

Bagci³

et al. 2012

AJNR Am J Neuroradiol

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BACKGROUND AND PURPOSE: Impaired CSF homeostasis and altered venous hemodynamics are proposed mechanisms for elevated pressure in IIH. However, the lack of ventricular expansion steered the focus away from CSF homeostasis in IIH. This study aims to measure intracranial CSF volumes and cerebral venous drainage with MR imaging to determine whether increased CSF volume from impaired CSF homeostasis and venous hemodynamics occur in obesity-related IIH.

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3D Slicer

Cited by 350 publications

References 0 publications

Intraosseous stress distribution and bone interaction during load application across the canine elbow joint: A preliminary finite element analysis for determination of condylar fracture pathogenesis in immature and mature dogs

Intraosseous stress distribution and bone interaction during load application across the canine elbow joint: A preliminary finite element analysis for determination of condylar fracture pathogenesis in immature and mature dogs

Recurrent glioblastoma: Volumetric assessment and stratification of patient survival with early posttreatment magnetic resonance imaging in patients treated with bevacizumab

MRI Evidence of Impaired CSF Homeostasis in Obesity-Associated Idiopathic Intracranial Hypertension

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