3D Printing for scaphoid-reconstruction with medial femoral condyle flap

Schmidt, Manfred; Holzbauer, Matthias; Kwasny, O.; Huemer, Georg M.; Froschauer, Stefan M.

doi:10.1016/j.injury.2020.02.102

Cited by 14 publications

(9 citation statements)

References 12 publications

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“…Thus, we were considering current methods for metacarpal reconstruction: the commonly applied techniques involve both non-vascularized and vascularized autologous bone flaps from the fibula, the iliac crest or the distal radius for smaller defects [ 10 ]. Recently, MFC represents an increasingly utilized donor site, where free vascularized osteochondral [ 7 ] or corticocancellous microvascular bone flap up to a maximal length of 13.7 cm [ 11 ] can be harvested.…”

Section: Discussionmentioning

confidence: 99%

“…Recently, haptic, 3 D-printed models on the basis of CT data have emerged as novel, intraoperative assistant devices improving the surgeons’ 3D perception while performing intricate, surgical procedures [ 7 ]. In our particular case, 3D models were used for three purposes: First, the model enabled a functional verification of the flap size while placing it into the metacarpal defect, even before the final MFC flap dissection, harvesting etc.…”

Section: Discussionmentioning

confidence: 99%

“…It has also been reported for partial metacarpal reconstruction [ 6 ]. Three-dimensional (3D) printed models have recently been described as an innovative technology for facilitating MFC flap harvest and for precise tailoring of the required bone flap [ 7 ].…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Metacarpal reconstruction with a medial femoral condyle flap based on a 3D-printed model: a case report

Schmidt

Holzbauer

Froschauer

2022

Case Reports in Plastic Surgery and Hand Surgery

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Metacarpal reconstruction with a medial femoral condyle flap based on a 3D-printed model: a case report

Schmidt

Holzbauer

Froschauer

2022

Case Reports in Plastic Surgery and Hand Surgery

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“…Unfortunately, greater than 10% of these fractures progress to non-union [50], which must be treated with bone autografts. Due to the intricate structure and patient-specific shape of the scaphoid bone, 3D printing has been proposed as a clinical tool for the treatment of these fractures and for use in pre-operative planning [51], reconstructive microsurgery [52], and the printing of patient-specific ceramic implants [53]. To (figure 7(l-n)).…”

Section: Alginate-cacl 2 Can Be Used For Printing Anatomically Accuramentioning

confidence: 99%

Evaluation of Alginate-Based Bioinks for 3D Bioprinting, Mesenchymal Stromal Cell Osteogenesis, and Application for Patient-Specific Bone Grafts

Fernández

Tenorio

Campbell

et al. 2020

Preprint

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To realize the promise of 3D bioprinting, it is imperative to develop bioinks that possess the biological and rheological characteristics needed for the printing of cell-laden tissue grafts. Alginate is widely used as a bioink because its rheological properties can be modified through pre-crosslinking or the addition of thickening agents to increase printing resolution. However, modification of alginate's physicochemical characteristics using common crosslinking agents can affect its cytocompatibility. Therefore, we evaluated the printability, physicochemical properties, and osteogenic potential of four common alginate bioinks: alginate-CaCl2 (alg-CaCl2), alginate-CaSO4 (alg-CaSO4), alginate-gelatin (alg-gel) and alginate-nanocellulose (alg-ncel) for the 3D bioprinting of patient-specific osteogenic grafts. While all bioinks possessed similar viscosity, printing fidelity was lower in the pre-crosslinked bioinks. When used to print geometrically defined constructs, alg-CaSO4 and alg-ncel exhibited higher mechanical properties and lower mesh size than those printed with alg-CaCl2 or alg-gel. The physical properties of these constructs affected the biological performance of encapsulated bone marrow-derived mesenchymal stromal cells (MSCs). Cell-laden constructs printed using alg-CaSO4 and alg-ncel exhibited greater cell apoptosis and contained fewer living cells 7 days post-printing. In addition, effective cell-matrix interactions were only observed in alg-CaCl2 printed constructs. When cultured in osteogenic media, MSCs in alg-CaCl2 constructs exhibited increased osteogenic differentiation compared to the other three bioinks. This bioink was then used to 3D print anatomically accurate cell-laden scaphoid bones that were capable of partial mineralization after 14 days of in vitro culture. These results highlight the importance of bioink properties to modulate cell behavior and the biofabrication of clinically relevant bone tissues.

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“…Three-dimensional (3D) printing techniques are evolving, and their application in medical technology, such as utilizing it to make artificial bone flaps for various surgeries is increasing, 11,12) . This study aimed to analyze the outcomes of using a customized artificial skull bone flap made by a 3D printing technique for cranioplasty, compared with autobone.…”

mentioning

confidence: 99%

Clinical Outcomes of Cranioplasty Using a Customized Artificial Bone Flap Made by a 3D Printing Technique

Lee

Shim

Kim

et al. 2021

J Neurointensive Care

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Cranioplasty is required to restore the appearance of the skull, ObjectiveTo analyze the outcomes of using a customized artificial skull bone flap made with a three-dimensional (3D) printing technique for cranioplasty and compare them with those of the autobone technique. MethodBetween December 2018 and February 2020, 24 cranioplasties were performed for 24 hemispheres using a customized artificial bone flap made by 3D printing. Simultaneously, 19 cranioplasties for 19 hemispheres were performed using an autobone. Three patients underwent cranioplasty using both a customized artificial bone flap and autobone for each hemisphere. Patient's demographics, reason for craniectomy, interval between craniectomy and cranioplasty, surface area of the skull defect and bone flap, bone flap coverage of the defect, cranioplasty-related factors, and clinical outcome were assessed. ResultsForty patients who underwent cranioplasty (bone flap, 21; autobone flap, 16; and artificial bone/ autobone flaps, 3) were enrolled. The artificial bone flap covered more skull defects than the autobone flap (98.6% vs. 90.9%, p=0.000). There were two and six operation-related complications in the artificial bone flap and autobone flap groups, respectively (P=0.061). The subtemporal area was completely covered in the artificial bone flap group. Two patients had an infection of the autobone flap and had it replaced by a 3D printing flap. No patient showed a reduction in the modified Rankin Scale score after surgery, and the clinical course was confirmed to have improved. ConclusionsCranioplasty using customized artificial bone flap made by 3D printing technique was effective for covering the skull defect and tends to have a low complication rate compared to the autobone.

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3D Printing for scaphoid-reconstruction with medial femoral condyle flap

Cited by 14 publications

References 12 publications

Metacarpal reconstruction with a medial femoral condyle flap based on a 3D-printed model: a case report

Metacarpal reconstruction with a medial femoral condyle flap based on a 3D-printed model: a case report

Evaluation of Alginate-Based Bioinks for 3D Bioprinting, Mesenchymal Stromal Cell Osteogenesis, and Application for Patient-Specific Bone Grafts

Clinical Outcomes of Cranioplasty Using a Customized Artificial Bone Flap Made by a 3D Printing Technique

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