3D Printing Applied to Tissue Engineered Blood Grafts

Wenger, Raphaël; Giraud, Marie-Noëlle

doi:10.20944/preprints201811.0590.v1

Cited by 6 publications

(4 citation statements)

References 66 publications

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“…The gold standard for vascular grafting is represented by autologous arteries and veins. Autograft arteries such as the internal thoracic artery and the radial artery (Wenger andGiraud, 2018, Fukunishi et al, 2017), are associated with superior patency, with 10-year rates of 90% (Pashneh-Tala et al, 2015, Tara et al, 2014. However, due to the limited availability of arteries and the severe complications related to their removal, the most commonly used autologous vessel is the saphenous vein (Pashneh-Tala et al, 2015), with a 10-year patency rate of 50% (Tara et al, 2014).…”

Section: Autografts and Allograftsmentioning

confidence: 99%

“…The use of autografts is associated with several disadvantages of which the lack of natural grafts for patients who need multiple grafting is the most important (Wenger and Giraud, 2018). Autografting often results in failure after 10 years due to poor quality, size mismatches, and atherosclerosis (Fukunishi et al, 2017, Pashneh-Tala et al, 2015.…”

Section: Autografts and Allograftsmentioning

confidence: 99%

“…Non-degradable polymers, including polyethylene terephthalate (PET and Dacron), polytetrafluoroethylene (Gore-Tex), and expanded polytetrafluoroethylene (ePTFE) are the common choices for synthetic vascular grafting for vessels larger than 6 mm in diameter, such as the aortic, iliac, and common femoral arteries (Wenger and Giraud, 2018, Chang and Niklason, 2017, Love, 2017. These biomaterials exhibit several advantages, such as biocompatibility, low risk of thrombosis, tunable size and form, cost-effectiveness, and ease of surgical handling due to their adequate mechanical properties in terms of compliance and blood flow resistance (Wenger and Giraud, 2018). The manufacturing techniques involve knitting or weaving through which suitable pore sizes that allow for a certain radial blood permeation along with the axial perfusion can be achieved.…”

Section: Biomaterials For Vascular Tissue Engineering 321 Synthetimentioning

confidence: 99%

“…However, intima hyperplasia, thrombosis, and infection affect the long-term patency of these grafts. Due to the differences regarding the mechanical properties of native tissues and synthetic grafts, blood flow disturbances and wall shear stress will lead to endothelial injuries and, consequently, to vascular failure (Wenger and Giraud, 2018).…”

Section: Biomaterials For Vascular Tissue Engineering 321 Synthetimentioning

confidence: 99%

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Tissue engineered vascular grafts

2018

Biomater Tissue Eng Bull

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With the continuous increase in the prevalence of cardiovascular diseases and the limited efficiency of conventional treatments, including diet and lifestyle modifications, pharmaceutical administration, and surgical interventions, there is an equally increased need for vascular grafts for the replacement of damaged blood vessels. Currently, autologous grafts represent the gold standard. However, due to the limited availability, intensive work has been performed in the field of vascular tissue engineering. Although there are many possibilities for obtaining synthetic vascular grafts, there is still no ideal solution for vascular replacements. In this paper, the main material categories and fabrication techniques are reviewed.

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Section: Autografts and Allograftsmentioning

confidence: 99%

Section: Autografts and Allograftsmentioning

confidence: 99%

Section: Biomaterials For Vascular Tissue Engineering 321 Synthetimentioning

confidence: 99%

Section: Biomaterials For Vascular Tissue Engineering 321 Synthetimentioning

confidence: 99%

See 2 more Smart Citations

Tissue engineered vascular grafts

2018

Biomater Tissue Eng Bull

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3D Bioprinting Strategies for the Regeneration of Functional Tubular Tissues and Organs

et al. 2020

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It is difficult to fabricate tubular-shaped tissues and organs (e.g., trachea, blood vessel, and esophagus tissue) with traditional biofabrication techniques (e.g., electrospinning, cell-sheet engineering, and mold-casting) because these have complicated multiple processes. In addition, the tubular-shaped tissues and organs have their own design with target-specific mechanical and biological properties. Therefore, the customized geometrical and physiological environment is required as one of the most critical factors for functional tissue regeneration. 3D bioprinting technology has been receiving attention for the fabrication of patient-tailored and complex-shaped free-form architecture with high reproducibility and versatility. Printable biocomposite inks that can facilitate to build tissue constructs with polymeric frameworks and biochemical microenvironmental cues are also being actively developed for the reconstruction of functional tissue. In this review, we delineated the state-of-the-art of 3D bioprinting techniques specifically for tubular tissue and organ regeneration. In addition, this review described biocomposite inks, such as natural and synthetic polymers. Several described engineering approaches using 3D bioprinting techniques and biocomposite inks may offer beneficial characteristics for the physiological mimicry of human tubular tissues and organs.

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Recent Advancements in 3D Printing and Bioprinting Methods for Cardiovascular Tissue Engineering

et al. 2021

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Recent decades have seen a plethora of regenerating new tissues in order to treat a multitude of cardiovascular diseases. Autografts, xenografts and bioengineered extracellular matrices have been employed in this endeavor. However, current limitations of xenografts and exogenous scaffolds to acquire sustainable cell viability, anti-inflammatory and non-cytotoxic effects with anti-thrombogenic properties underline the requirement for alternative bioengineered scaffolds. Herein, we sought to encompass the methods of biofabricated scaffolds via 3D printing and bioprinting, the biomaterials and bioinks recruited to create biomimicked tissues of cardiac valves and vascular networks. Experimental and computational designing approaches have also been included. Moreover, the in vivo applications of the latest studies on the treatment of cardiovascular diseases have been compiled and rigorously discussed.

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3D Printing Applied to Tissue Engineered Blood Grafts

Cited by 6 publications

References 66 publications

Tissue engineered vascular grafts

Tissue engineered vascular grafts

3D Bioprinting Strategies for the Regeneration of Functional Tubular Tissues and Organs

Recent Advancements in 3D Printing and Bioprinting Methods for Cardiovascular Tissue Engineering

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