3D Printing and Personalized Airway Stents

Cheng, George Z.; Folch, Erik; Wilson, Adam; Brik, Robert; Garcia, Noah; Estépar, Raúl San Jośe; Onieva, Jorge Onieva; Gangadharan, Sidhu P.; Majid, Adnan

doi:10.1007/s41030-016-0026-y

Cited by 36 publications

(13 citation statements)

References 27 publications

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“…3D printing technology has recently been approved by the Food and Drug Administration (FDA) for customized printing of stents. It has been gaining some use in Europe (17) and is also thought to slowly start gaining momentum in NA after its FDA approval. Individual tailored stents are preferable over customizing purchased airway stents.…”

Section: Resultsmentioning

confidence: 99%

Tracheobronchial stent sizing and deployment practices airway stenting practices around the world: a survey study

et al. 2020

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Background: Tracheobronchial stents types, uses, techniques for deployment and extraction have practice variations around the world. Methods: We collected responses by sending an online survey of 8 questions to world interventional bronchology member societies and social media groups. Results: There were 269 respondents from 47 countries. Europe had 97 respondents from 22 countries. There were 8 respondents from Australia, 7 from Africa (3 countries) and 7 from 4 countries in South America (SA). North America (NA) had 72 respondents from 3 countries. Asia had 78 respondents from 14 countries. For stent placements 15% [41] used fiberoptic bronchoscope (FB) only. Rigid bronchoscopy (RB) was solely utilized by 38% [102]. Forty-six percent [123] used a combination of RB and FB (P value <0.00001). For stent extraction 13% [19] used FB alone, 57% [85] used RB, and 36% [54] used a combination of RB and FB (P value <0.00001). Placement of stents were 50.5% [135] only by direct visualization. Twentythree percent [61] always used fluoroscopic guidance. Twenty-six-point-five percent [71] used fluoroscopy in certain cases (P value <0.00001). Sixty percent [162] decided stent sizing by measurements of stenotic and non-stenotic areas on radiology. Twelve percent [32] respondents used sizing devices. Sixty-five percent [177] used a ruler and bronchoscope to measure stenotic areas. Thirty-eight percent [104] used visual estimation and experience. Seven percent [19] used serial balloon dilatation size. To prevent clogging of stents, 22% [59] prescribed mucolytics. Seventy-three percent [195] nebulized saline, 26% [70] had Mucomyst Nebulization, 24% [65] Nebulized bronchodilators and other methods 11% [30] were advised. Covered self-expandable metal stents (SEMS) 44% was the commonest type of stent used around the world. Silicone stents 37%, Y stents 15%, uncovered SEMS 12%, Montgomery T tube 5% followed. Polyflex stents 3% and custommade stents 3% were least used. Biodegradable stents were used by 7.5%, and not used by 92.5%. Conclusions: Tracheobronchial stent practice norms have slowly evolved, but its practice variations lack uniformity, and have sparse evidence-based studies for its direction.

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Section: Resultsmentioning

confidence: 99%

Tracheobronchial stent sizing and deployment practices airway stenting practices around the world: a survey study

et al. 2020

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“…The trachea for example demonstrates circumferential rigidity, imparted by sequential fibrocartilage rings, and longitudinal flexibility, provided by an elastic ECM between the sequential rings 16 . This anisotropic structure is essential to tissue function as it allows the trachea to stretch or compress longitudinally during neck extension and adduction but prevents radial collapse during the pressure drops that occur while coughing or taking a deep breath 17 , 18 .…”

Section: Resultsmentioning

confidence: 99%

Surface tension-assisted additive manufacturing

Ragelle

Tibbitt

et al. 2018

Nat Commun

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The proliferation of computer-aided design and additive manufacturing enables on-demand fabrication of complex, three-dimensional structures. However, combining the versatility of cell-laden hydrogels within the 3D printing process remains a challenge. Herein, we describe a facile and versatile method that integrates polymer networks (including hydrogels) with 3D-printed mechanical supports to fabricate multicomponent (bio)materials. The approach exploits surface tension to coat fenestrated surfaces with suspended liquid films that can be transformed into solid films. The operating parameters for the process are determined using a physical model, and complex geometric structures are successfully fabricated. We engineer, by tailoring the window geometry, scaffolds with anisotropic mechanical properties that compress longitudinally (~30% strain) without damaging the hydrogel coating. Finally, the process is amenable to high cell density encapsulation and co-culture. Viability (>95%) was maintained 28 days after encapsulation. This general approach can generate biocompatible, macroscale devices with structural integrity and anisotropic mechanical properties.

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“…The construction industry is increasingly using AM for topology optimisation, customised parts, in situ repair, and tolerance matching [7]. Additive manufacturing is also used in medical applications such as printing customised airway stents and soft prostheses [8] [9]. Due to the unique capabilities of AM, it is possible to manufacture optimised parts which would traditionally be non-trivial to produce.…”

Section: Related Workmentioning

confidence: 99%

Direct-Write Fabrication of Wear Profiling IoT Sensor for 3D Printed Industrial Equipment

Munasinghe¹,

Miles²,

Paul³

2019

Proceedings of the International Symposium on Automation and Robotics in Construction (IAARC)

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Additive Manufacturing (AM), also known as 3D printing, is an emerging technology, not only as a prototyping technology, but also to manufacture complete products. Gravity Separation Spirals (GSS) are used in the mining industry to separate slurry into different density components. Currently, spirals are manufactured using moulded polyurethane on fibreglass substructure, or injection moulding. These methods incur significant tooling cost and lead times making them difficult to customise, and they are labour-intensive and can expose workers to hazardous materials. Thus, a 3D printer is under development that can print spirals directly, enabling mass customisation. Furthermore, sensors can be embedded into spirals to measure the operational conditions for predictive maintenance, and to collect data that can improve future manufacturing processes. The localisation of abrasive wear in the GSS is an essential factor in optimising parameters such as suitable material, print thickness, and infill density and thus extend the lifetime and performance of future manufactured spirals. This paper presents the details of a wear sensor, which can be 3D printed directly into the spiral using conductive material. Experimental results show that the sensor can both measure the amount of wear and identify the location of the wear in both the horizontal and vertical axes. Additionally, it is shown that the accuracy can be adjusted according to the requirements by changing the number and spacing of wear lines.

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3D Printing and Personalized Airway Stents

Cited by 36 publications

References 27 publications

Tracheobronchial stent sizing and deployment practices airway stenting practices around the world: a survey study

Tracheobronchial stent sizing and deployment practices airway stenting practices around the world: a survey study

Surface tension-assisted additive manufacturing

Direct-Write Fabrication of Wear Profiling IoT Sensor for 3D Printed Industrial Equipment

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