3D‐Printed Soft Lithography for Complex Compartmentalized Microfluidic Neural Devices

Kajtez, Janko; Buchmann, Sebastian; Vasudevan, Shashank; Birtele, Marcella; Rocchetti, Stefano; Pless, Christian Jonathan; Heiskanen, Arto; Barker, Roger A.; Martínez‐Serrano, Alberto; Parmar, Malin; Lind, Johan; Emnéus, Jenny

doi:10.1002/advs.202101787

Advanced Science

2021

DOI: 10.1002/advs.202101787

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3D‐Printed Soft Lithography for Complex Compartmentalized Microfluidic Neural Devices

Janko Kajtez¹,

Sebastian Buchmann²,

Shashank Vasudevan³

et al.

Abstract: In the originally published article, some information was missing in the acknowledgements. Please find the correct acknowledgements here:

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Advancing diagnostics and disease modeling: current concepts in biofabrication of soft microfluidic systems

Casanova,

Reis

et al. 2024

In vitro models

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Soft microfluidic systems play a pivotal role in personalized medicine, particularly in in vitro diagnostics tools and disease modeling. These systems offer unprecedented precision and versatility, enabling the creation of intricate three-dimensional (3D) tissue models that can closely emulate both physiological and pathophysiological conditions. By leveraging innovative biomaterials and bioinks, soft microfluidic systems can circumvent the current limitations involving the use of polydimethylsiloxane (PDMS), thus facilitating the development of customizable systems capable of sustaining the functions of encapsulated cells and mimicking complex biological microenvironments. The integration of lab-on-a-chip technologies with soft nanodevices further enhances disease models, paving the way for tailored therapeutic strategies. The current research concepts underscore the transformative potential of soft microfluidic systems, exemplified by recent breakthroughs in soft lithography and 3D (bio)printing. Novel applications, such as multi-layered tissues-on-chips and skin-on-a-chip devices, demonstrate significant advancements in disease modeling and personalized medicine. However, further exploration is warranted to address challenges in replicating intricate tissue structures while ensuring scalability and reproducibility. This exploration promises to drive innovation in biomedical research and healthcare, thus offering new insights and solutions to complex medical challenges and unmet needs.

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Advancing diagnostics and disease modeling: current concepts in biofabrication of soft microfluidic systems

Casanova,

Reis

et al. 2024

In vitro models

View full text Add to dashboard Cite

show abstract

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3D‐Printed Soft Lithography for Complex Compartmentalized Microfluidic Neural Devices

Abstract: In the originally published article, some information was missing in the acknowledgements. Please find the correct acknowledgements here:

Cited by 1 publication

References 35 publications

Advancing diagnostics and disease modeling: current concepts in biofabrication of soft microfluidic systems

Advancing diagnostics and disease modeling: current concepts in biofabrication of soft microfluidic systems

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