3D paper-based microfluidic device: a novel dual-detection platform of bisphenol A

Yukird, Jutiporn; Soum, Veasna; Kwon, Oh‐Sun; Shin, Kwanwoo; Chailapakul, Orawon; Rodthongkum, Nadnudda

doi:10.1039/c9an01738k

Cited by 39 publications

(13 citation statements)

References 48 publications

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“…Paper-based sensors can be perfectly integrated with electrochemical techniques [35]. These combined systems enable the integration of different electrodes, such as ion-selective or microelectrodes [36,37]. They provide signal amplification while working in flow injection systems.…”

Section: Introductionmentioning

confidence: 99%

Paper-Based Electrochemical Biosensors for Voltammetric Detection of miRNA Biomarkers Using Reduced Graphene Oxide or MoS2 Nanosheets Decorated with Gold Nanoparticle Electrodes

et al. 2021

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Paper-based biosensors are considered simple and cost-efficient sensing platforms for analytical tests and diagnostics. Here, a paper-based electrochemical biosensor was developed for the rapid and sensitive detection of microRNAs (miRNA-155 and miRNA-21) related to early diagnosis of lung cancer. Hydrophobic barriers to creating electrode areas were manufactured by wax printing, whereas a three-electrode system was fabricated by a simple stencil approach. A carbon-based working electrode was modified using either reduced graphene oxide or molybdenum disulfide nanosheets modified with gold nanoparticle (AuNPs/RGO, AuNPs/MoS2) hybrid structures. The resulting paper-based biosensors offered sensitive detection of miRNA-155 and miRNA-21 by differential pulse voltammetry (DPV) in only 5.0 µL sample. The duration in our assay from the point of electrode modification to the final detection of miRNA was completed within only 35 min. The detection limits for miRNA-21 and miRNA-155 were found to be 12.0 and 25.7 nM for AuNPs/RGO and 51.6 and 59.6 nM for AuNPs/MoS2 sensors in the case of perfectly matched probe-target hybrids. These biosensors were found to be selective enough to distinguish the target miRNA in the presence of single-base mismatch miRNA or noncomplementary miRNA sequences.

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Section: Introductionmentioning

confidence: 99%

Paper-Based Electrochemical Biosensors for Voltammetric Detection of miRNA Biomarkers Using Reduced Graphene Oxide or MoS2 Nanosheets Decorated with Gold Nanoparticle Electrodes

et al. 2021

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“…Several paper-based devices utilizing zinc or its compounds have been developed to detect different analytes or toxins in food. Yukird et al [59] deposited zinc oxide from a solution over 2 detection zones in a paper-based device. The first was a multiwall carbon nanotube electrode and the second was a laser desorption ionization mass spectrometric detection zone.…”

Section: Food Safetymentioning

confidence: 99%

Literature Review of the Use of Zinc and Zinc Compounds in Paper-Based Microfluidic Devices

Charbaji¹,

Heidari-Bafroui²,

Anagnostopoulos³

et al. 2021

JMMCE

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Zinc and its compounds, alloys and composites play an important role in the modern day world and find application in almost every aspect that can improve the quality of our lives. This ranges from supplements and pharmaceuticals that are meant to improve our health and wellbeing to additives meant to guard or reduce corrosion in metals. However, over the past several years, a new area of technology has been garnering a great deal of attention and has made use of zinc and its compounds. This is with reference to paper-based microfluidic technology that offers several advantages and that keeps expanding in the amount of applications it covers. In this paper, a review is offered for the applications that have used zinc or zinc compounds in paper-based microfluidic devices.

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“…The inkjet printing may require several or single printing time(s) to pattern good conductive electrodes because it can only print low viscosity ink (1–40 cP), which depends on the type of paper and inkjet printer used for the fabrication [ 109 , 110 ]. Lastly, the ballpoint pen printing method was reported that it could print conductive electrodes on photo paper within a single printing time [ 111 , 112 ]. A recent review paper by Noviana et al has summarized methods for the fabrication of electrochemical paper-based devices [ 21 ].…”

Section: Fabrication Of µPadsmentioning

confidence: 99%

Recent Advances in Microfluidic Paper-Based Analytical Devices toward High-Throughput Screening

et al. 2020

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Microfluidic paper-based analytical devices (µPADs) have become promising tools offering various analytical applications for chemical and biological assays at the point-of-care (POC). Compared to traditional microfluidic devices, µPADs offer notable advantages; they are cost-effective, easily fabricated, disposable, and portable. Because of our better understanding and advanced engineering of µPADs, multistep assays, high detection sensitivity, and rapid result readout have become possible, and recently developed µPADs have gained extensive interest in parallel analyses to detect biomarkers of interest. In this review, we focus on recent developments in order to achieve µPADs with high-throughput capability. We discuss existing fabrication techniques and designs, and we introduce and discuss current detection methods and their applications to multiplexed detection assays in relation to clinical diagnosis, drug analysis and screening, environmental monitoring, and food and beverage quality control. A summary with future perspectives for µPADs is also presented.

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3D paper-based microfluidic device: a novel dual-detection platform of bisphenol A

Abstract: A novel platform of 3D paper-based microfluidic device (μPADs) was fabricated by a digital plotter for high precision analysis of bisphenol A using electrochemistry along with LDI-MS detection.

Cited by 39 publications

References 48 publications

Paper-Based Electrochemical Biosensors for Voltammetric Detection of miRNA Biomarkers Using Reduced Graphene Oxide or MoS2 Nanosheets Decorated with Gold Nanoparticle Electrodes

Paper-Based Electrochemical Biosensors for Voltammetric Detection of miRNA Biomarkers Using Reduced Graphene Oxide or MoS2 Nanosheets Decorated with Gold Nanoparticle Electrodes

Literature Review of the Use of Zinc and Zinc Compounds in Paper-Based Microfluidic Devices

Recent Advances in Microfluidic Paper-Based Analytical Devices toward High-Throughput Screening

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