3D Non-Destructive Fluorescent X-Ray Computed Tomography With a CdTe Array

Yoon, Changyeon; Kim, Younghak; Lee, Wonho

doi:10.1109/tns.2016.2565478

Cited by 9 publications

(3 citation statements)

References 28 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…One way to accomplish the aforementioned goal is through parallel acquisition of XRF signals using a 2D array of single-crystal detectors or a pixelated detector. Early experimental investigations provided preliminary insight into the advantages (e.g., reduced XFCT scan time) and disadvantages (e.g., reduced system sensitivity) from using 1D or 2D pixelated photon counting detectors for benchtop XFCT [6][7][8]. Similar advantages and disadvantages were also noted in recent benchtop XFCT/XRF mapping studies of live animals [9,10] using pixelated photon counting detectors and pinhole collimators.…”

Section: Introductionmentioning

confidence: 71%

Characterization of a Pixelated Cadmium Telluride Detector System Using a Polychromatic X-Ray Source and Gold Nanoparticle-Loaded Phantoms for Benchtop X-Ray Fluorescence Imaging

Jayarathna¹,

Ahmed²,

O'ryan³

et al. 2021

IEEE Access

View full text Add to dashboard Cite

show abstract

Section: Introductionmentioning

confidence: 71%

Characterization of a Pixelated Cadmium Telluride Detector System Using a Polychromatic X-Ray Source and Gold Nanoparticle-Loaded Phantoms for Benchtop X-Ray Fluorescence Imaging

Jayarathna¹,

Ahmed²,

O'ryan³

et al. 2021

IEEE Access

View full text Add to dashboard Cite

show abstract

“…While readily available, typical pixelated photon-counting detectors provide only a limited number (~4-5) of rather broad energy bins/windows (in a few keV intervals) and, consequently, may not meet the detector specifications for ideal benchtop XFCT imaging. Nevertheless, there have been attempts to adopt some of them for benchtop XFCT (Yoon et al 2016, Ren et al 2016, providing some insight into the technical feasibility and reconfirming some benefits of benchtop XFCT previously demonstrated (e.g. better sensitivity than transmission CT) (Bazalova et al 2012, Manohar et al 2016.…”

Section: Advances In Science and Technology To Meet Challengesmentioning

confidence: 88%

Roadmap for metal nanoparticles in radiation therapy: current status, translational challenges, and future directions

Schuemann¹,

Bagley²,

Berbeco³

et al. 2020

Phys. Med. Biol.

110

View full text Add to dashboard Cite

show abstract

“…In recent years, research efforts have been given to the adoption of various pixelated photon counting detectors for benchtop XRF/XFCT imaging (Ren et al 2016, Yoon et al 2016, Li et al 2017, Zhang et al 2019, Jung et al 2020. More recently, the use of fully spectroscopic two dimensional (2D)/pixelated semiconductor detector systems has also been suggested for the same purpose (Schuemann et al 2020, Zannoni et al 2020.…”

Section: Introductionmentioning

confidence: 99%

Bias-voltage dependent operational characteristics of a fully spectroscopic pixelated cadmium telluride detector system within an experimental benchtop x-ray fluorescence imaging setup

Moktan¹,

Panta²,

Cho³

2021

Biomed. Phys. Eng. Express

View full text Add to dashboard Cite

Commercially available fully spectroscopic pixelated cadmium telluride (CdTe) detector systems have been adopted lately for benchtop x-ray fluorescence (XRF) imaging/computed tomography (XFCT) of objects containing metal nanoprobes such as gold nanoparticles (GNPs). To date, however, some important characteristics of such detector systems under typical operating conditions of benchtop XRF/XFCT imaging systems are not well known. One important but poorly studied characteristic is the effect of detector bias-voltage on photon counting efficiency, energy resolution, and the resulting material detection limit. In this work, therefore, we investigated these characteristics for a commercial pixelated detector system adopting a 1-mm-thick CdTe sensor (0.25-mm pixel-pitch), known as HEXITEC, incorporated into an experimental benchtop cone-beam XFCT system with parallel-hole detector collimation. The detector system, operated at different bias-voltages, was used to acquire the gold XRF/Compton spectra from 1.0 wt% GNP-loaded phantom irradiated with 125 kVp x-rays filtered by 1.8-mm Tin. At each bias-voltage, the gold XRF signal, and the full-width-at-half-maximum at gold Kα 2 XRF peak (∼67 keV) provided photon counting efficiency and energy resolution, respectively. Under the current experimental conditions, the detector photon counting efficiency and energy resolution improved with increasing bias-voltage by ∼41 and ∼29% at −300V; ∼54 and ∼35% at −500V, respectively, when compared to those at −100V. Consequently, the GNP detection limit improved by ∼26% at −300V and ∼30% at −500V. Furthermore, the homogeneity of per-pixel energy resolution within the collimated detector area improved by ∼34% at −300V and ∼54% at −500V. These results suggested the gradual improvements in the detector performance with increasing bias-voltage up to −500V. However, at and beyond −550V, there were no discernible improvements in photon counting efficiency and energy resolution. Thus, the bias-voltage range of −500 to −550V was found optimal under the current experimental conditions that are considered typical of benchtop XRF/XFCT imaging tasks.

show abstract

3D Non-Destructive Fluorescent X-Ray Computed Tomography With a CdTe Array

Cited by 9 publications

References 28 publications

Characterization of a Pixelated Cadmium Telluride Detector System Using a Polychromatic X-Ray Source and Gold Nanoparticle-Loaded Phantoms for Benchtop X-Ray Fluorescence Imaging

Characterization of a Pixelated Cadmium Telluride Detector System Using a Polychromatic X-Ray Source and Gold Nanoparticle-Loaded Phantoms for Benchtop X-Ray Fluorescence Imaging

Roadmap for metal nanoparticles in radiation therapy: current status, translational challenges, and future directions

Bias-voltage dependent operational characteristics of a fully spectroscopic pixelated cadmium telluride detector system within an experimental benchtop x-ray fluorescence imaging setup

Contact Info

Product

Resources

About