3D MR colonography after intravenous administration of the hepatobiliary contrast agent Gd-BOPTA: bile tagging

Knopp, Michael V.; Giesel, F.L.; Tengg-Kobligk, Hendrik von

doi:10.1007/s10406-004-0068-3

Cited by 2 publications

(1 citation statement)

References 2 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Dark-lumen MRC is based on focal uptake of T1-shortening contrast material in colonic lesions, which are displayed as bright areas on T1-weighted sequences, whereas the lumen is rendered totally dark due to material with long T1 relaxation times, such as water or oral barium or gastrografin [20,21]. Thus, gadolinium-enhanced MRI of the bowel has been shown to be more accurate than unenhanced MRI and has also advantages over T2-weighted MRI [22].…”

Section: Discussionmentioning

confidence: 98%

Magnetic resonance colonography without bowel cleansing using oral and rectal stool softeners (fecal cracking)—a feasibility study

et al. 2005

View full text Add to dashboard Cite

The aim of our study was to assess the effect of oral and rectal stool softeners on dark-lumen magnetic resonance (MR) colonography without bowel cleansing. Ten volunteers underwent MR colonography without colonic cleansing. A baseline examination was performed without oral or rectal administration of stool softeners. In a second set, volunteers ingested 60 ml of lactulose 24 h prior to MR examination. In a third examination, water as a rectal enema was replaced by a solution of 0.5%-docusate sodium (DS). A fourth MR examination was performed, in conjunction with both oral administration of lactulose and rectal application of DS. A T1-weighted data set was acquired at scanning times of 0, 5 and 10 min after colonic filling. A fourth data set was acquired 75 s after i.v. injection of contrast agent. Signal intensity of stool was calculated for all colonic segments. Without oral ingestion of lactulose or rectal enema with DS stool signal intensity was high and did not decrease over time. However, lactulose and DS caused a decrease in stool signal intensity. Both substances together led to a decreasing signal intensity of feces. Combination of lactulose and DS provided the lowest signal intensity of stool. Thus, feces could hardly be distinguished from dark rectal enema allowing for the assessment of the colonic wall.

show abstract

Section: Discussionmentioning

confidence: 98%