3D model simulation on magnetic induction spectroscopy for fetal acidosis detection using COMSOL multiphysics

A Review on Magnetic Induction Spectroscopy Potential for Fetal Acidosis Examination

“…Therefore, 10 MHz was used to plot voltage versus pH ( Figure 25 ) by applying formula where is the output voltage, G is the phase shift minus 90° phase shift, and 0.01 is the attenuation. This result is supported by the magnetic field versus pH plot which is also found to decrease as the pH value increases [ 19 ]. The Rx signal sensitivity is defined as the slope of the fitted straight line, which varies with pH.…”

“…These risks are increased in fetuses with suspected hemophilia or thrombocytopenia [ 15 ] and in mothers with HIV, hepatitis B, or C [ 3 ]. In addition, the analysis requires a large amount of blood (30–50 uL) and is time consuming (median time taken is 18 min) [ 19 ], resulting in diagnostic delay while pH drops at a rate 0.01–0.04 unit/min [ 20 , 21 ]. Prolonged collection time increases the risk of blood clotting and clogging the analyzer [ 22 ].…”

“…Increasing the concentration also creates an acidic condition in the tissue and lowers the pH. Therefore, an increase in pH value causes a decrease in both the magnetic field and conductivity [ 19 ]. This proves that magnetic fields and conductivity are inversely proportional to pH values [ 65 ].…”