2020
DOI: 10.1002/lsm.23262
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3D Mesh Releasing Method: A Retrospective Analysis of Fractional CO2 Treatment on Contracture Scars

Abstract: Background and Objectives There has been reports on fractional CO2 laser successfully improving contracture scars that impair the function of a joint. It seems that certain contracture problems could be solved by laser instead of surgery. However, the clinical application could be difficult when the efficacy of the method remains unknown. The purpose of this study is to report the releasing capacity of the fractional CO2 laser on contracture scars based on a defined treatment method. Study Design/Materials and… Show more

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Cited by 5 publications
(23 citation statements)
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“…Second, posttreatment collagen rearrangement changed the flexibility and texture of the scar, preventing further progression and joint dysfunction and conferring a therapeutic advantage. CO 2 laser treatment is also effective on contracted scars, and the treatment effect lasts at least 6 months [ 33 ]. In our study, the earliest laser treatment took place 4 weeks after injury, and the recipient did not show joint dysfunction even after a 1-year follow-up.…”
Section: Discussionmentioning
confidence: 99%
“…Second, posttreatment collagen rearrangement changed the flexibility and texture of the scar, preventing further progression and joint dysfunction and conferring a therapeutic advantage. CO 2 laser treatment is also effective on contracted scars, and the treatment effect lasts at least 6 months [ 33 ]. In our study, the earliest laser treatment took place 4 weeks after injury, and the recipient did not show joint dysfunction even after a 1-year follow-up.…”
Section: Discussionmentioning
confidence: 99%
“…(1,2) Bacterial vaginosis (BV), the most common (30%) cause of vaginal discharge in women of reproductive age, is a type of dysbiosis marked by reduced Lactobacillus and an overgrowth of anaerobic species, including Gardnerella, Fannyhessea vaginae, and Prevotella. (2)(3)(4) Clinically, BV is characterized by symptoms such as vaginal discharge, a fish-like odor, and increased vaginal pH. Although its exact cause is unclear, BV is linked to serious health issues, including complications during pregnancy and a heightened risk of sexually transmitted and urogenital infections.…”
Section: Exploring the Efficacy And Clinician Experience Withmentioning
confidence: 99%
“…Therefore, it is necessary to develop better treatment alternatives for BV. (2,4) Antimicrobial blue light (aBL; 400 -470 nm wavelength) may be an effective approach for this challenge; it is a 'drug-free' approach to microbial killing, with potent microbicidal effects and a high selectivity for bacteria over mammalian cells. (8) The widely accepted hypothesis for aBL-mediated killing involves the photoexcitation of endogenous porphyrins, leading to the generation of intracellular reactive oxygen species (ROS) that cause membrane damage, DNA damage, lipid peroxidation, and more.…”
Section: Exploring the Efficacy And Clinician Experience Withmentioning
confidence: 99%
“…Dr. Zhang mentioned that such minimal-invasiveness modality could potentially serve as a supplement to the current treatment ladder for contracture scars. 41 Laser therapies' effects on scar therapy are induced by disrupting the high blood flow in the scars, decreasing fibroblast proliferation, type III collagen deposition, and histamine release. Fractional laser therapy stimulates a wound healing response that involves heat shock proteins and myofibroblasts, resulting in promoting scar remodeling.…”
Section: Laser Therapies Integrated In Treating Pathological Scarsmentioning
confidence: 99%
“…Dr. Zhang mentioned that such minimal-invasiveness modality could potentially serve as a supplement to the current treatment ladder for contracture scars. 41 …”
Section: Introductionmentioning
confidence: 99%