3D high-definition manometry in evaluation of children after surgery for Hirschsprung's disease: A pilot study

Banasiuk, Marcin; Banaszkiewicz, Aleksandra; Piotrowski, Dariusz; Albrecht, Piotr; Kamiński, Andrzej; Radzikowski, Andrzej

doi:10.1016/j.advms.2015.07.008

Cited by 20 publications

(47 citation statements)

References 26 publications

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“…For 3DARM, normal values have been published in 4 articles: 2 included adults, one primigravid women during the first trimester of pregnancy, and one children only . However, there is no published study that has evaluated the utility of 3DARM in patients with anorectal symptoms.…”

Section: Introductionmentioning

confidence: 99%

3D High‐definition anorectal manometry: Values obtained in asymptomatic volunteers, fecal incontinence and chronic constipation. Results of a prospective multicenter study (NOMAD)

Mion

Garros

Brochard

et al. 2017

Neurogastroenterology Motil

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Section: Introductionmentioning

confidence: 99%

3D High‐definition anorectal manometry: Values obtained in asymptomatic volunteers, fecal incontinence and chronic constipation. Results of a prospective multicenter study (NOMAD)

Mion

Garros

Brochard

et al. 2017

Neurogastroenterology Motil

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“…JID: YJPSU [mNS; December 4, 2020;20:41 ] sure of the internal anal sphincter [3][4][5] . In addition, dyssynergic defecation can cause anal outlet obstruction [5] .…”

Section: Article In Pressmentioning

confidence: 99%

Intrasphincteric botulinum toxin injections for post-operative obstructive defecation problems in hirschsprung disease: A retrospective observational study

Roorda

Oosterlaan

Heurn

et al. 2020

Journal of Pediatric Surgery

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Background: Patients with Hirschsprung disease may have obstructive symptoms after resection of the aganglionic segment. Botulinum toxin (BT) injections can help improve faecal passage by relaxing the internal anal sphincter. This study assess effect of BT injections and aims to identify factors associated with receiving BT injections and favourable response to the first BT injection. Methods: A retrospective study was performed in a cohort of consecutive patients treated for Hirschsprung disease in our centre between 2003 and 2017. The indication for BT injections was obstructive defecation problems that were non-responsive to high-dose laxatives or rectal irrigation, or an episode of Hirschsprung-associated enterocolitis (HAEC). Effectiveness of BT injections was measured in terms of clinical improvement. Relationships between factors associated with receiving BT injections and with response to the first BT injection were tested with group comparison and logistic regression. Results: Forty-one out of 131 patients received BT injections (31%) with a median of two injections (range 1-11). All patients had obstructive defecation problems non-responsive to high-dose laxatives or rectal irrigation, two patient also had an episode of HAEC. Twenty-five out of 41 patients (61%) had clinical improvement after first injection. In 29 of the 41 patients (71%) spontaneous defecation or treatment with laxatives only was achieved. Adverse effects were seen in 12 out of 41 patients (29%) after 14 injections (16%), and consisted of anal pain, temporary loss of stools and dermatitis. Patients who received BT injections more often had long segment disease, more often required laxatives or rectal irrigation and had longer length of hospital stay, both after corrective surgery and in follow-up. None of the tested factors was associated with clinical improvement after first BT injection. Conclusion: Our findings show that BT injections effectively treat obstructive defecation problems in the majority of patients with Hirschsprung disease with mild adverse effects.

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“…Evaluation of RAIR can also be useful in children with suspected anal achalasia. The RAIR is classically absent in patients with Hirschsprung's disease, anal sphincter achalasia and after circular rectal myomectomy or complex imperforate anus repair. To evaluate patients with anorectal malformations with persistent defecation problems after surgical repair. To assess persistent defecation problems after surgery for Hirschsprung's disease . Because the anal sphincter is dysfunctional in all children with Hirschsprung's disease and the RAIR remains absent after surgery, patients can experience difficult stool expulsion and chronic constipation.…”

Section: Indicationsmentioning

confidence: 99%

“…Hirschsprung's disease. 38,39 Because the anal sphincter is dysfunctional in all children with Hirschsprung's disease and the RAIR remains absent after surgery, patients can experience difficult stool expulsion and chronic constipation. In patients with Hirschsprung's disease with fecal incontinence following surgical repair the measurement of the length of the anal canal may be of relevance.…”

Section: To Assess Persistent Defecation Problems After Surgery Formentioning

confidence: 99%

An ANMS‐NASPGHAN consensus document on anorectal and colonic manometry in children

Rodriguez

Sood

Lorenzo

et al. 2016

Neurogastroenterology Motil

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175

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3D high-definition manometry in evaluation of children after surgery for Hirschsprung's disease: A pilot study

Cited by 20 publications

References 26 publications

3D High‐definition anorectal manometry: Values obtained in asymptomatic volunteers, fecal incontinence and chronic constipation. Results of a prospective multicenter study (NOMAD)

3D High‐definition anorectal manometry: Values obtained in asymptomatic volunteers, fecal incontinence and chronic constipation. Results of a prospective multicenter study (NOMAD)

Intrasphincteric botulinum toxin injections for post-operative obstructive defecation problems in hirschsprung disease: A retrospective observational study

An ANMS‐NASPGHAN consensus document on anorectal and colonic manometry in children

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